3.10 Combined Morphological and Functional Investi...
Secretin-enhanced magnetic resonance cholangiopancreatography（S-MRCP）reveals ductal morphological alterations and simultaneously gives semi-quantitative information on functional changes by evaluation of the degree of duodenal filling（Balci et al.2010）.However，the number of appropriate studies is small and the sensitivity of this technique for pancreatic exocrine insufficiency appears to be limited（about 70%）（Schneider et al.2006；Bilgin et al.2008）.Thus，normal duodenal filling does not rule out pancreatic exocrine insufficiency（Martinez et al.2013）.Endoscopic ultrasonography has recently also been combined with secretin-stimulation.Similar to S-MRCP，fluidfilling in the descending part of duodenum was a predictor of pancreatic insufficiency（Engjom et al.2015）but clinical usefulness of this method needs to be further evaluated.(https://www.daowen.com)