六、治疗

无特殊治疗，对症治疗，必要时手术治疗。

参考文献

［1］Lu C M，MacDougall M.RIG-I-like receptor signaling in singleton-merten syndrome［J］.Frontiers in Genetics，2017，8：118.

［2］Lu C M，Mamaeva O A，Cui C，et al.Establishment of Singleton-Merten Syndrome pulp cells：Evidence of mineralization dysregulation［J］.Connective Tissue Research，2014，55（supl）：57-61.(https://www.daowen.com)

［3］Feigenbaum A，Müller C，Yale C，et al.Singleton-Merten syndrome：An autosomal dominant disorder with variable expression［J］.American Journal of Medical Genetics Part A，2013，161（2）：360-370.

［4］Buers I，Rice G I，Crow Y J，et al.MDA5-associated neuroinflammation and the singleton-merten syndrome：Two faces of the same type I interferonopathy spectrum［J］.Journal of Interferon & Cytokine Research，2017，37（5）：214-219.

［5］Pettersson M，Bergendal B，Norderyd J，et al.Further evidence for specific IFIH1 mutation as a cause of Singleton-Merten syndrome with phenotypic heterogeneity［J］.American Journal of Medical Genetics Part A，2017，173（5）：1396-1399.

（王翔　王文梅）