Treatment
Treatment is divided into 3 stages：
Firstly，induction therapy for 2 weeks.
Secondly，consolidation therapy for 8 weeks.
Lastly，maintenance therapy.
（1）Induction therapy：
Daily prehydration with litre normal saline containing a vial of potassium chloride（given over 2 hours）for 7 days—if there is no potassium chloride with an intravenous drip，patient can take potassium which absorbs slowly three times each day.
Daily amphotericin B 1 mg/kg in a litre 5%dextrose was given at least over 4 hours for 5 days.
Take pills of fluconazole 1200 mg for 14 days
Daily method of spinal taps therapeutic（releasing the CSF up to 20 mL per puncture）.
（2）consolidation therapy：
Fluconazole 400 mg/day for 42 days.
（3）maintenance therapy：
fluconazole 200 mg/day for life.
（4）important therapy：
①Patient who has a raised intracranial pressure need daily carry out LP until the intracranial pressure is normal.(https://www.daowen.com)
②If patient deteriorate with severe headache，vomiting，low GCS should recheck opening pressure！
③If patient has a therapy of ARV for more than 6 months already，check viral load for treatment failure.
④If patient has not a therapy of ARV yet，they should start ARV therapy after the commencing the treatment of Cryptococcal Meningitis for one month.（if ARV was started too early，life-threatening IRIS may occur）.
⑤If patient is on TB treatment，you should adjust the dose of fluconazole.
Abbreviations
CSF：脑脊液
sub-acute：亚急性的
LP（lumber puncture）：腰穿
ARV（antiretroviral）：抗反转录病毒药物
GCS（Glasgow come scale）：格拉斯哥评分
IRIS（epileptic seizure）：癫痫发作
Glasgow coma scale
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