Endocrine Function Tests of Chronic Pancreatitis

Song Su，and Mao-Jin Xu(https://www.daowen.com)

According to American Pancreatic Association Practice Guidelines，endocrine function tests in the diagnosis of chronic pancreatitis（CP）is of limited values.In patients with CP，diabetes mellitus is one of the most common metabolic diseases caused by pancreatic endocrine dysfunction.Diabetes mellitus together with mild pancreas imaging morphology or recurrent pseudocyst/pancreatitis can only give probable evidence instead of definitive evidence（Conwell et al.2014；Sze et al.2014）.The relationship between CP and diabetes mellitus is complicated.For the sake of obesity or metabolic syndrome，some patients with earlier stages of CP develop type 2 diabetes mellitus（T2DM）.Patients with type 1 diabetes mellitus（T1DM）for a long time can also have CP，but the mechanism of this phenomenon is scarcely known（Chen et al.2011；Cui and Andersen 2011）.Considering the high prevalence and incidence of endocrine dysfunction，physicians should pay great attention to diabetes mellitus secondary to CP and detect it as an essential component of the complete diagnosis of CP.