1.1　Life Style Changes

Continued alcohol consumption can trigger recurrent attacks of acute pancreatitis，and aggressive alcohol intervention can definitely benefit patients from recurrence（Yadav 2011）.Immoderate alcohol consumption is also thought as a definite risk factor.Although the incidence and prevalence of CP are low，it increased greatly because of the alcohol consumption and nearly 50%are alcohol related（Yadav et al.2011）.Alcohol impairs cystic fibrosis transmembrane conductance regulator（CFTR）activity and may explain a mechanism for pancreatitis（Park 2016）.It was recommended that alcohol cessation improved the course of CP（Gurusamy et al.2016a）.The damage of alcohol can be long lasting as pancreatic functional continuously decreased even after cessation of alcohol use，however the pathological change was slower and less severe（Gullo et al.1998）.Results from observational studies have noticed that smoking is an established risk factor for all forms of pancreatitis and the risk increases in a dose-dependent fashion.When combing cigarette smoking and alcohol consumption，the pathophysiologic effects can be multiplied（Greer et al.2015）.Thus smoking and drinking should be discouraged（Luaces-Regueira et al.2014）.It is reported that smoking cessation can improve the patients’quality of life（Han et al.2016）and reduce the risk of developing pancreatic calcifications in the first years from the clinical onset of CP（Talamini et al.2007）.(https://www.daowen.com)