Acknowledgements

The authors are indebted to Drs.Stella Knight，Steve Macatonia，Valerie Ng，Brian Hjelle，Judy Wilber and Luc Montagnier for helpful discussion.We are grateful to Joe Brewer and Project Inform for their support，and we also thank Steven Koontz and Kevin Cox for expert technical assistance.

Supported in part by Research Grants 89.024C and 90.041C from California Pacific Medical Center and the Elizabeth Reed Taylor Foundation.(https://www.daowen.com)