Acknowledgements

Supported in part by Research Grants 89.024C and 90.041C from California Pacific Medical Center and the Elizabeth Reed Taylor Foundation.

The authors thank Drs.Judy Wilber，Valerie Ng，Giuseppe Pantaleo and Anthony Fauci for helpful discussion.We are indebted to Cecilio Dumlao and Joanna Van Elk for sample collection and processing，and we are grateful to Steven Koontz and Lori Sanchez for expert technical assistance.(https://www.daowen.com)