2.3　Intraductal Carcinoma of Breast

2.3　Intraductal Carcinoma of Breast

Intraductal carcinoma of breast occurs in lobular unit of terminal duct.The basement membrane of the catheter is intact.There is no interstitial infiltration.Clinically，it is often asymptomatic，or part of the nipple may overflow.Ultrasonic manifestations are mainly mass type and gland structure disorder type.Some of them are only small clusters of fine calcification ultrasound，which is easy to be missed diagnosis.

Case 15：female，40 years old，has been found with left breast mass for more than one month.Specialized examination：No obvious abnormality is found in the breasts，and there is no overflow of liquid or blood on both nipples.

Fig.A　Maximum diameter section，low echo lesion，finecalcification

Fig.B　Transverse section，no regular shape，clear boundary

Fig.C　Alder grade 2

Fig.D　RI：0.45

Fig.E　The elasticity score is 4 points

Analysis and differential diagnosis：Left breast of middle-aged woman touches a hard mass.Ultrasonic manifestations：hypoechoic mass with irregular shape and unclear edge.Multiple fine calcifications can be seen in it.Abundant blood flow signals can be seen inside，Alder grade 3，elasticity score：4 It is consistent with the ultrasound manifestations of breast malignant tumors.(https://www.daowen.com)

Pathological results：During the operation，the tumor has no capsule，and the section is solid gray and gray red.It supports intraductal cancer Class Ⅲ.

Case 16：female，46 years old，has been found right breast lump for more than 1 month.Specialized examination：the upper quadrant outside the right breast can touch the mass，which is hard and has unclear boundary and can move freely.

Fig.A　Hypoechoic lesion with disordered structure

Fig.B　Multiple fine calcifications are found in the lesions

Fig.C　Irregular shape and unclear boundary

Fig.D　Alder grade 2

Analysis：The right breast of middle-aged woman touches a hard mass.Ultrasonic manifestations：The catheter's walking area is an abnormal echo area with irregular shape，unclear boundary，hypoecho inside，multiple fine calcifications inside，and no change in rear echo.CDFI：Abnormal，band-shaped blood flow signal can be seen inside，Alder grade 2.First of all，we should consider the lesion of catheter origin and the possibility of intraductal cancer.

Pathological results：During the operation，it is found that the tumor does not invade the pectoralis major fascia，and the section is solid gray and gray red.It supports for intraductal cancer class Ⅲ.