3.5　Mucinous Carcinoma

Term：Also known as gelatinous carcinoma，it is a rare type of invasive breast cancer that originates from the ductal epithelium of the breast and is characterized by a large amount of extracellular mucus production.

Clinical manifestation：

●Longer clinical course and slow tumor growth

●Palpation is mostly a lump with a clear boundary and a tough texture

●The location of mucinous adenocarcinoma is mostly in the upper quadrant of the breast，just like other invasive ductal carcinomas.

●Misdiagnosed as benign tumor

Population distribution characteristics：

●Mucinous cancer accounts for 1%～7%of all breast cancer

●≥75 years old women account for 7%，≤35 years old women account for 1%

Mammography：

●Round，oval or lobulated，irregular high-density lumps

●Simple mucinous carcinoma：border clear or tiny lobulated

●Mixed mucinous carcinoma：blurred edges，infiltrating or burr-like changes

MR：

●T1W1 edge is smooth or fuzzy，oval or micro-lobular tumor，signal intensity is affected by mucus protein components，with equal and low signal performance

●T2W1 fat suppression phase，simple type mucinous carcinoma：homogeneously distinctly highsignal；mixed mucinous carcinoma：homogeneous or heterogeneous high signal(https://www.daowen.com)

●Progressive reinforcement

●DWI showed a high signal and the ADC value was higher，which was significantly higher than the malignant tumors of the breasts including various pathological types we have previously summarized.

●Continuous or platform hemodynamic curve

Image inspection recommended：

●Best image inspection method：MR

Case 1