Chapter Ⅶ Targeted Therapy for Breast Cancer
Breast cancer is a complex heterogeneous disease that is the most common tumor that harms women's health.At present,there are many chemotherapy drugs for the treatment of breast cancer,but they all have shortcomings such as poor selectivity,heavy side effects,and easy drug resistance,resulting in a low 5-year survival rate for breast cancer patients.With the development of molecular biology technology,people have become more and more thorough and thorough understanding of the occurrence and development of tumors at the molecular level.Targeted therapies targeting key genes,cell receptors,and regulatory molecules are becoming more widely and clinically.(https://www.daowen.com)
Molecular targeted therapy is a new treatment.The so-called molecular targeted therapy is to design a corresponding therapeutic drug at the molecular level of the molecule against a well-defined carcinogenic site(which may be a protein molecule inside the tumor cell or a gene fragment).After entering the body,it will only specifically bind to these carcinogenic sites and act,resulting in tumor cell-specific death,and will not affect the normal tissue cells around the tumor,so molecular targeted therapy is also called“biological Missile”.Molecular targeted therapy for breast cancer is another effective medical treatment after chemotherapy and endocrine therapy.