8.3.5 Case Report
Case 1.Female，53 years old
She was admitted to hospital in October 2018.Modified radical mastectomy was performed on 2018/11/01.Ⅰ-Ⅱ grade（mass size 2cm×1cm），intraductal carcinoma with focal intraductal carcinoma（about 20%of intraductal carcinoma）and axillary lymph nodes（10/21）were detected after operation.Immunohistochemical：ER（was about 70%+），PR（about 80%+），Cerb-B2（2+），FISH showed that HER-2 gene was not amplified，Ki-67（about 10%+）.
Postoperative diagnosis：pT2N3M0 ⅢC stage of invasive ductal carcinoma in the upper quadrant of left breast.
EC sequential T regimen chemotherapy was performed for 8 cycles after operation.
2019-07-10 operated postoperative radiotherapy，irradiation range and dose：left chest wall left upper and lower clavicle lymph node area，left internal mammary lymph node area，DT 50 Gy/25F，2 Gy/F.
Case 2.Female，35 years old(https://www.daowen.com)
Diagnosis：pT2N1M0 ⅡB stage Luminal A after chemotherapy in left extramammary inferior quadrant invasive ductal carcinoma
Pathological diagnosis：2018-10-29“left breast mass puncture biopsy”.Pathological report：left breast puncture tissue（X201813553）：intraductal carcinoma with invasive carcinoma.Immunohistochemistry：the expression of invasive ductal carcinoma：ER（about 60%+），PR（about 60%+）and Cer-B2（+），Ki-67（about 10%）.“radical surgery for left breast cancer（sentinel lymph node biopsy for left breast cancer）was performed on 2018/10/31，and pathological report（B201810609）was diagnosed after operation（B201810609）.”radical surgery for left breast cancer（Sentinel lymph node biopsy for left breast cancer）was performed，and the pathological report（B201810609）was diagnosed as follows：（cut edge of left breast mass）Invasive carcinoma（size：2.5×1.0 cm），Immuno-histoche-mistry group：ER（medium+，80%），PR（medium+，80%），HER2（1+），ki-67（10%），supporting Ⅱ grade of invasive ductal carcinoma，no cancer was found on each incisor.Sentinel lymph nodes（1/5）showed cancer metastasis.
Case 3.Female，46 years old
Diagnosis：Luminal A in cT1N1MO IA stage after low grade intraductal carcinoma of left breast.
Auxiliary examination：2018/10/23 pathological diagnosis：left breast fiber cysticercosis with local ductal epithelial atypical hyperplasia.Combined with the results of immunohistochemistry，（left breast）fibrocystic breast disease，with common ductal hyperplasia and hyperhidrosis，cyst formation and inflammatory cell infiltration，flat epithelial atypical hyperplasia in small foci，atypical ductal hyperplasia and low grade intraductal carcinoma.The expression of intraductal carcinoma：ER（3+about 90%），PR（3+，about 90%），Cerb-B2（1+），ki-67（+，＜1%）.