参考文献

参考文献

[1]Lancaster M A,Renner M,Martin C A,et al.Cerebral organoids model human brain development and microcephaly.Nature,2013,501:373-379.

[2]Tuveson D,Clevers H.Cancer modeling meets human organoid technology.Science,2019,364:952-955.

[3]Sachs N,de Ligt J,Kopper O,et al.A living biobank of breast cancer organoids captures disease heterogeneity.Cell,2018,172:373-386.

[4]Vlachogiannis G,Hedayat S,Vatsiou A,et al.Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.Science,2018,359:920-926.

[5]Boretto M,Maenhoudt N,Luo X,et al.Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.Nat Cell Biol,2019,21:1041-1051.

[6]Lynch H T,Snyder C L,Shaw T G,et al.Milestones of Lynch syndrome:1895-2015.Nat Rev Cancer,2015,15:181-194.

[7]Yao X,Smolka A J.Gastric parietal cell physiology and Helicobacter pylori-Induced disease.Gastroenterology,2019,156:2158-2173.

[8]Skardal A,Shupe T,Atala A.Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling.Drug Discov Today,2016,21:1399-1411.

[9]Mo X,Niu Q,Ivanov A A,et al.Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.Cell,2022,185:1974-1985.

[10]Yao X.Modeling cellular polarity,plasticity,and disease disparity in 4D.J Mol Cell Biol,2020,12:559-561.

[11]Hiratsuka K,Miyoshi T,Kroll K T,et al.Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery.Sci Adv,2022,8:eabq0866.

[12]Kimura M,Iguchi T,Iwasawa K,et al.En masse organoid phenotyping informs metabolicassociated genetic susceptibility to NASH.Cell,2022,185:4216-4232.

[13]Bhaduri A,Andrews M G,Kriegstein A R,et al.Are organoids ready for prime time?Cell Stem Cell,2020,27:361-365.

[14]Rajasekar S,Lin D S Y,Abdul L,et al.IFlow Plate-a customized 384-well plate for the culture of perfusable vascularized colon organoids.Adv Mater,2020,32:e2002974.

[15]Sakurai M,Ishitsuka K,Ito R,et al.Chemically defined cytokine-free expansion of human haematopoietic stem cells.Nature,2023,615:127-133.(https://www.daowen.com)

[16]Bouffi C,Wikenheiser-Brokamp K A,Chaturvedi P,et al.In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.Nat Biotechnol,2023.

[17]Koh V,Chakrabarti J,Torvund M,et al.Hedgehog transcriptional effector GLI mediates m TOR Induced PD L1 expression in gastric cancer organoids.Cancer Lett,2021,518:59-71.

[18]Kuen J,Darowski D,Kluge T,et al.Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model.PLoS One,2017,12:e0182039.

[19]Grebenyuk S,Ranga A.Engineering organoid vascularization.Front Bioeng Biotechnol,2019,7:39.

[20]Mansour A A,Goncalves J T,Bloyd C W,et al.An in vivo model of functional and vascularized human brain organoids.Nat Biotechnol,2018,36:432-441.

[21]Shi Y,Sun L,Wang M,et al.Vascularized human cortical organoids(v Organoids)model cortical development in vivo.PLoS Biol,2020,18:e3000705.

[22]Wang Y,Takeishi K,Li Z,et al.Microenvironment of a tumor-organoid system enhances hepatocellular carcinoma malignancy-related hallmarks.Organogenesis,2017,13:83-94.

[23]Shirure V S,Bi Y,Curtis M B,et al.Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids.Lab Chip,2018,18:3687-3702.

[24]Low J H,Li P,Chew E G Y,et al.Generation of human PSC-derived kidney organoids with patterned nephron segments and a de novo vascular network.Cell Stem Cell,2019,25:373-387.

[25]Qian X,Nguyen H N,Song M M,et al.Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure.Cell,2016,165:1238-1254.

[26]Rowe R G,Daley G Q.Induced pluripotent stem cells in disease modelling and drug discovery.Nat Rev Genet,2019,20:377-388.

[27]Bhaduri A,Andrews M G,Mancia Leon W,et al.Cell stress in cortical organoids impairs molecular subtype specification.Nature,2020,578:142-148.

[28]Dijkstra K K,Cattaneo C M,Weeber F,et al.Generation of tumor-reactive T cells by co-culture of peripheral blood lymphocytes and tumor organoids.Cell,2018,174:1586-1598.

[29]Bock C,Boutros M,Camp J G,et al.The organoid cell atlas.Nat Biotechnol,2021,39:13-17.

[30]Brancati G,Treutlein B,Camp J G.Resolving neurodevelopmental and vision disorders using organoid single-cell multi-omics.Neuron,2020,107:1000-1013.