口腔颌面部异常的相关治疗建议
通常,由于缺乏相关的全身并发症或恶性转化,LHS不需要治疗。基于美学考虑,患者可寻求治疗以去除唇色素沉着斑块。治疗可以选择冷冻手术,调Q的Nd:YAG激光和调Q的紫翠宝石激光。治疗后可能会复发。防晒是防止再次发生的关键。
参考文献
[1]Duan N,Zhang Y H,Wang W M,et al.Mystery behind labial and oral melanotic macules:Clinical,dermoscopic and pathological aspects of Laugier-Hunziker syndrome[J].World J Clin Cases,2018,6(10):322-334.
[2]Wei,Z,Li G Y,Ruan H H,et al.Laugier-hunziker syndrome:a case report.Journal of Stomatology Oral & Maxillofacial Surgery,2018,119(2):158-160.
[3]Wang W M,Wang X,Duan N,et al.Laugier-Hunziker syndrome:a report of three cases and literature review.Int J Oral,2012,4(4):226-230.
[4]王翔,王文梅,高雅凡,等.Laugier-Hunziker综合征40例临床分析[J].临床口腔医学杂志,2015,31(11):674-676.(https://www.daowen.com)
[5]Fernandes D,Ferrisse T M,Navarro C M,et al.Pigmented lesions on the mucosa:a wide range of diagnoses[J].Oral Surg Oral Med Oral Pathol Oral Radiol,2015,119(4):374-378.
[6]Cusick E H,Marghoob A A,Braun R P.Laugier-Hunziker syndrome:a case of asymptomatic mucosal and acral hyperpigmentation[J].Dermatol Pract Concept,2017,7(30):27-30.
[7]Nayak R S,Kotrashetti V S,Hosmani J V.Laugier-Hunziker syndrome[J].J Oral Maxillofac Pathol,2012,16(2):245-250.
[8]Zuo Y G,Ma D L,Jin H Z,et al.Treatment of Laugier-Hunziker syndrome with the Q-switched alexandrite laser in 22 Chinese patients[J].Arch Dermatol Res,2010,302(2):125-130.
(段宁 王文梅)