附录十： 美国环保署预防、农药及有毒物质办公室和OECD测试导则列表

第一部分 美国环保署预防、农药及有毒物质办公室测试导则列表

OPPTS Harmonized Test Guidelines(series 850 Ecological Effects Test Guidelines)

Group B-Terrestrial Wildlife

850.2000-Background and Special Considerations-Tests with Terrestrial Wildlife(June2012)

850.2100-Avian Acute Oral toxicity Test(June2012)

850.2200-Avian Dietary toxicity Test(June2012)

850.2300-Avian Reproduction Test(June2012)

850.2400-Wild Mammal toxicity Testing(June2012)

850.2500-Field Testing for Terrestrial Wildlife(June2012)

Group C-Terrestrial Beneficial Insects,Invertebrates, and Soil and Wastewater Microorganisms

850.3000-Background and Special Considerations-Tests with Terrestrial Beneficial Insects,Invertebrates and Microorganisms(June2012)

850.3020-Honey Bee Acute Contact toxicity Test(June2012)

850.3030-Honey Bee toxicityof Residueson Foliage(June2012)

850.3040-Field Testing for Pollina tors(June2012)

850.3100-Earthworm Subchronic toxicity Test(June2012)

850.3200-Soil Microbial Community toxicity Test(June2012)

850.3300-Modified Activated Sludge,Respiration Inhibition Test(June 2012)

Group D-Terrestrial and Aquatic Plants,Cyanobacteria, and Terrestrial Soil Core Microcosm

850.4000-Background and Special Considerations-Tests with Terrestrial and Aquatic Plants,Cyanobacteria, and Terrestrial Soil-Core Microcosms (June2012)

850.4100-Seedling Emergence and Seedling Growth(June2012)

850.4150-Vegetative Vigor(June2012)

850.4230-Early Seedling Growth toxicity Test(June2012)

850.4300-Terrestrial Plants Field Study(June2012)

850.4400-Aquatic Plant toxicity Test Using Lemnaspp.(June2012)

850.4450-Aquatic Plants Field Study(June2012)

850.4500-Algal toxicity(June2012)

850.4550-Cyanobacteria(Anabaenaflos-aquae) toxicity(June2012)

850.4600-Rhizobium-Legume toxicity(June2012)

850.4800-Plant Uptake and Translocation Test(June2012)

850.4900-Terrestrial Soil-Core Microcosm Test(June2012)

Group F-Field Test Data Reporting Guidelines

850.6100-Environmental Chemistry Methods and Associated Independent Labora tory Validation(June2012)

Link:http://www.epa.gov/ocspp/pubs/frs/publications/Test_Guidelines/se-ries850.htm

OPPTSHarmonized Test Guidelines(series870Health Effects Test Guidelines)

Supplemental Guidance

Test Guidelines/Acute toxicity-Acute Oral toxicity Up- and -Down-Pro-cedure

Guidance for Waivingor Bridgingof Mammalian Acute toxicity Tests for Pesticides and Pesticide Products

Guidance for Neuro toxicity Battery,Subchronic Inhalation,Subchronic Dermal and Immuno toxicity Studies

Genetic toxicology:Integrationofinvivo Testingin to St and ard Repeat Dose Studies

Useofan Alternate Testing Framework for Classificationof Eye Irrita-tion Potentialof EPAPesticide Products

Updateonthe Useofthe Local Lymph Node Assay for End Use Pesticide Products and Adoptionofthe Reduced Dose Pro tocol for LLNA(r LLNA)

Group A-Acute toxicity Test Guidelines

870.1000-Acute toxicity Testing-Background(December2002)

870.1100-Acute Oral toxicity(December2002)

870.1200-Acute Dermal toxicity(August1998)

870.1300-Acute Inhalation toxicity(August1998)

870.2400-Acute Eye Irritation(August1998)

870.2500-Acute Dermal Irritation(August1998)

870.2600-Skin Sensitization(March2003)

Group B-Subchronic toxicity Test Guidelines

870.3050-Repeated Dose28-Day Oral toxicity Studyin Rodents(July 2000)

870.3100-90-Day Oral toxicityin Rodents(August1998)

870.3150-90-Day Oral toxicityin Non-rodents(August1998)

870.3200-21/28-Day Dermal toxicity(August1998)

870.3250-90-Day Dermal toxicity(August1998)

870.3465-90-Day Inhalation toxicity(August1998)

870.3550-Reproduction/Developmental toxicity Screening Test(July 2000)

870.3650-Combined Repeated Dose toxicity Study withthe Reproduc-tion/Developmental toxicity Screening Test(July2000)

870.3700-Prenatal Developmental toxicity Study(August1998)

870.3800-Reproduction and Fertility Effects(August1998)

Group C-Chronic toxicity Test Guidelines

870.4100-Chronic toxicity(August1998)

870.4200-Carcinogenicity(August1998)

870.4300-Combined Chronic toxicity/Carcinogenicity(August1998)

Group D-Genetic toxicity Test Guidelines

870.5100-Bacterial Reverse Mutation Test(August1998)

870.5140-Gene Mutationin Aspergillusnidulans(August1998)

870.5195-Mouse Biochemical Specific Locus Test(August1998)

870.5200-Mouse Visible Specific Locus Test(August1998)

870.5250-Gene Mutationin Neurosporacrassa(August1998)

870.5275-Sex-linked Recessive Lethal Testin Drosophilamelanogaster (August1998)

870.5300-Invitro Mammalian Cell Gene Mutation Test(August1998) 870.5375-Invitro Mammalian Chromosome Aberration Test(August 1998)

870.5380-Mammalian Sperma togonial Chromosomal Aberration Test (August1998)

870.5385-Mammalian Bone Marrow Chromosomal Aberration Test(Au-gust1998)

870.5395-Mammalian Erythrocyte Micronucleus Test(August1998)

870.5450-Rodent Dominant Lethal Assay(August1998)

870.5460-Rodent Heritable Translocation Assays(August1998)

870.5500-Bacterial DNADamageor Repair Tests(August1998)

870.5550-Unscheduled DNASynthesisin Mammalian Cellsin Culture (August1998)

870.5575-Mi totic Gene Conversionin Saccharomycescerevisiae(August 1998)

870.5900-Invitro Sister Chromatid Exchange Assay(August1998)

870.5915-Invivo Sister Chromatid Exchange Assay(August1998)

Group E-Neuro toxicity Test Guidelines

870.6100-Acute and 28-Day Delayed Neuro toxicityof Organophosphorus Substances(August1998)

870.6200-Neuro toxicity Screening Battery(August1998)

870.6300-Developmental Neuro toxicity Study(August1998)

870.6500-Schedule-Controlled Operant Behavior(August1998)

870.6850-Peripheral Nerve Function(August1998)

870.6855-Neurophysiology Sensory Evoked Potentials(August1998)

Group F-Special Studies Test Guidelines

870.7200-Companion Animal Safety(August1998)

870.7485-Metabolism and Pharmacokinetics(August1998)

870.7600-Dermal Penetration(August1998)

870.7800-Immuno toxicity(August1998)

Group G-Health Effects Chemical-Specific Test Guidelines

870.8355-Combined Chronic toxicity/Carcinogenicity Testingof Respira-ble Fibrous Particles(July2001)

Link:http://www.epa.gov/ocspp/pubs/frs/publications/Test_Guidelines/se-ries870.htm(下载于2014年12月31日)

第二部分：经济合作与发展组织（OECD）测试导则列表

OECDGuidelines forthe Testingof Chemicals,Section2Effectson Biotic Systems(https://www.daowen.com)

Summaryof Considerationsinthe Reportfromthe OECDExpert Group on Eco toxicology11-Sep-2006

Test No.201:Freshwater Alga and Cyanobacteria,Growth Inhibition Test28-Jul-2011

Test No.202:Daphniasp.Acute Immobilisation Test23-Nov-2004

Test No.203:Fish,Acute toxicity Test17-Jul-1992

Test No.204:Fish,Prolonged toxicity Test:14-Day Study4-Apr-1984 Test No.205:Avian Dietary toxicity Test4-Apr-1984

Test No.206:Avian Reproduction Test4-Apr-1984

Test No.207:Earthworm,Acute toxicity Tests4-Apr-1984

Test No.208:Terrestrial Plant Test:Seedling Emergence and Seedling Growth Test17-Aug-2006

Test No.209:Activated Sludge,Respiration Inhibition Test(Carbon and Ammonium Oxidation)23-Jul-2010

Test No.210:Fish,Early-life Stage toxicity Test26-Jul-2013

Test No.211:Daphniamagna Reproduction Test2-Oct-2012

Test No.212:Fish,Short-term toxicity Tes ton Embryo and Sac-Fry Stages21-Sep-1998

Test No.213:Honeybees,Acute Oral toxicity Test21-Sep-1998

Test No.214:Honeybees,Acute Contact toxicity Test21-Sep-1998

Test No.215:Fish,Juvenile Growth Test21-Jan-2000

Test No.216:Soil Microorganisms:Nitrogen Trans formation Test21-Jan-2000

Test No.217:Soil Microorganisms:Carbon Trans formation Test21-Jan-2000

Test No.218:Sediment-Water Chironomid toxicity Using Spiked Sedi-ment23-Nov-2004

Test No.219:Sediment-Water Chironomid toxicity Using Spiked Water 23-Nov-2004

Test No.220:Enchytraeid Reproduction Test23-Nov-2004

Test No.221:Lemnasp.Growth Inhibition Test11-Jul-2006

Test No.222:Earthworm Reproduction Test(Eiseniafetida/Eiseniaan-drei)23-Nov-2004

Test No.223:Avian Acute Oral toxicity Test23-Jul-2010

Test No.224:Determinationofthe Inhibitionofthe Activityof Anaero-bic Bacteria25-Jan-2007

Test No.225:Sediment-Water Lumbriculus toxicity Test Using Spiked Sediment15-Oct-2007

Test No.226:Preda torymite(Hypoaspis(Geolaelaps)aculeifer)repro-ductiontestinsoil16-Oct-2008

Test No.227:Terrestrial Plant Test:Vegetative Vigour Test17-Aug-2006

Test No.228:Determinationof Developmental toxicityofa Test Chemi-cal to Dipteran Dung Flies(Scathophagastercoraria L.(Scathophagidae), Muscaautumnalis De Geer(Muscidae))16-Oct-2008

Test No.229:Fish Short Term Reproduction Assay2-Oct-2012

Test No.230:21-day Fish Assay8-Sep-2009

Test No.231:Amphibian Metamorphosis Assay8-Sep-2009

Test No.232:Collembolan Reproduction Testin Soil8-Sep-2009

Test No.233:Sediment-Water Chironomid Life-Cycle toxicity Test Using Spiked Wateror Spiked Sediment23-Jul-2010

Test No.234:Fish Sexual Development Test28-Jul-2011

Test No.235:Chironomussp.,Acute Immobilisation Test28-Jul-2011 Test No.236:Fish Embryo Acute toxicity(FET)Test26-Jul-2013

Test No.237:Honey Bee(Apis Mellifera)Larval toxicity Test,Single Exposure26-Jul-2013

Test No.238:Sediment-Free Myriophyllum Spicatum toxicity Test26-Sep-2014

Link:http://www.oecd-ilibrary.org/environment/oecd-guidelines- for-the-testing-of-chemicals-section-2-effects-on-biotic-systems_20745761

OECDGuidelines forthe Testingof Chemicals,Section4Health Effects Summaryof Considerationsinthe Reportfromthe OECDExpert Groups on Short Term and Long Term toxicology11-Sep-06

Test No.401(obsoleted):Acute Oral toxicity24-Feb-1987(已废止)

Test No.402:Acute Dermal toxicity24-Feb-1987

Test No.403:Acute Inhalation toxicity8-Sep-2009

Test No.404:Acute Dermal Irritation/Corrosion24-Apr-2002

Test No.405:Acute Eye Irritation/Corrosion2-Oct-2012

Test No.406:Skin Sensitisation17-Jul-1992

Test No.407:Repeated Dose28-day Oral toxicity Studyin Rodents16-Oct-2008

Test No.408:Repeated Dose90-Day Oral toxicity Studyin Rodents21-Sep-1998

Test No.409:Repeated Dose90-Day Oral toxicity Studyin Non-Ro-dents21-Sep-1998

Test No.410:Repeated Dose Dermal toxicity:21/28-day Study12-May-1981

Test No.411:Subchronic Dermal toxicity:90-day Study12-May-1981 Test No.412:Subacute Inhalation toxicity:28-Day Study8-Sep-2009

Test No.413:Subchronic Inhalation toxicity:90-day Study8-Sep-2009 Test No.414:Prenatal Development toxicity Study22-Jan-2001

Test No.415:One-Generation Reproduction toxicity Study26-May-1983 Test No.416:Two-Generation Reproduction toxicity22-Jan-2001

Test No.417: toxicokinetics23-Jul-2010

Test No.418:Delayed Neuro toxicityof Organophosphorus Substances Following Acute Exposure27-Jul-1995

Test No.419:Delayed Neuro toxicityof Organophosphorus Substances:28-day Repeated Dose Study27-Jul-1995

Test No.420:Acute Oral toxicity-Fixed Dose Procedure8-Feb-2002

Test No.421:Reproduction/Developmental toxicity Screening Test27-Jul-1995

Test No.422:Combined Repeated Dose toxicity Study withthe Repro-duction/Developmental toxicity Screening Test22-Mar-1996

Test No.423:Acute Oral toxicity-Acute toxic Class Method8-Feb-2002 Test No.424:Neuro toxicity Studyin Rodents21-Jul-1997

Test No.425:Acute Oral toxicity:Up- and -Down Procedure16-Oct-2008

Test No.426:Developmental Neuro toxicity Study15-Oct-2007

Test No.427:Skin Absorption:In Vivo Method23-Nov-2004

Test No.428:Skin Absorption:In Vitro Method23-Nov-2004

Test No.429:Skin Sensitisation23-Jul-2010

Test No.430:In Vitro Skin Corrosion:Transcutaneous Electrical Resist-ance Test Method(TER)26-Jul-2013

Test No.431:In Vitro Skin Corrosion:Reconstructed Human Epidermis (Rhe)Test Method26-Sep-2014

Test No.432:In Vitro3T3NRUPho to toxicity Test23-Nov-2004

Test No.435:In Vitro Membrane Barrier Test Method for Skin Corro-sion17-Aug-2006

Test No.436:Acute Inhalation toxicity-Acute toxic Class Method8-Sep-2009

Test No.437:Bovine Corneal Opacity and Permeability Test Method for Identifyingi)Chemicals Inducing Serious Eye Damage and ii)Chemicals Not Requiring Classification for Eye Irritationor Serious Eye Damage26-Jul-2013 Test No.438:Isolated Chicken Eye Test Method for Identifyingi) Chemicals Inducing Serious Eye Damage and ii)Chemicals Not Requiring Clas-sification for Eye Irritationor Serious Eye Damage26-Jul-2013

Test No.439:In Vitro Skin Irritation-Reconstructed Human Epidermis Test Method26-Jul-2013

Test No.440:Uterotrophic Bioassayin Rodents15-Oct-2007

Test No.441:Hershberger Bioassayin Rats8-Sep-2009

Test No.442A:Skin Sensitization23-Jul-2010

Test No.442B:Skin Sensitization23-Jul-2010

Test No.443:Extended One-Generation Reproductive toxicity Study2-Oct-2012

Test No.451:Carcinogenicity Studies8-Sep-2009

Test No.452:Chronic toxicity Studies8-Sep-2009

Test No.453:Combined Chronic toxicity/Carcinogenicity Studies8-Sep-2009

Test No.455:Per formance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Recep tor Agonists2-Oct-2012

Test No.456:H295RSteroidogenesis Assay28-Jul-2011

Test No.457:BG1Luc Estrogen Recep tor Transactivation Test Method for Identifying Estrogen Recep tor Agonists and Antagonists2-Oct-2012

Test No.460:Fluorescein Leakage Test Method for Identifying Ocular Corrosives and Severe Irritants2-Oct-2012

Test No.471:Bacterial Reverse Mutation Test21-Jul-1997

Test No.473:In Vitro Mammalian Chromosomal Aberration Test26-Sep-2014

Test No.474:Mammalian Erythrocyte Micronucleus Test26-Sep-2014

Test No.475:Mammalian Bone Marrow Chromosomal Aberration Test 26-Sep-14

Test No.476:Invitro Mammalian Cell Gene Mutation Test21-Jul-1997 Test No.477:Genetic toxicology:Sex-Linked Recessive Lethal Testin Drosophilamelanogaster4-Apr-1984

Test No.478:Genetic toxicology:Rodent Dominant Lethal Test4-Apr-1984

Test No.479:Genetic toxicology:Invitro Sister Chromatid Exchange Assayin Mammalian Cells23-Oct-1986

Test No.480:Genetic toxicology:Saccharomycescerevisiae,Gene Mu-tation Assay23-Oct-1986

Test No.481:Genetic toxicology:Saacharomycescerevisiae,Miotic Re-combination Assay23-Oct-1986

Test No.482:Genetic toxicology:DNADamage and Repair,Unsched-uled DNASynthesisin Mammalian Cellsinvitro23-Oct-1986

Test No.483:Mammalian Sperma togonial Chromosome Aberration Test 21-Jul-1997

Test No.484:Genetic toxicology:Mouse Spot Test23-Oct-1986

Test No.485:Genetic toxicology,Mouse Heritable Translocation Assay 23-Oct-1986

Test No.486:Unscheduled DNASynthesis(UDS)Test with Mammali-an Liver Cellsinvivo21-Jul-1997

Test No.487:In Vitro Mammalian Cell Micronucleus Test26-Sep-2014 Test No.488:Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays26-Jul-2013

Test No.489:In Vivo Mammalian Alkaline Comet Assay26-Sep-2014

http://www.oecd-ilibrary.org/environment/oecd-guidelines- for-the-te-sting-of-chemicals-section-4-health-effects_20745788