Diagnosis
Have a history of History：hepatitis，schistosomiasis，hepatotoxic drugs（e.g.ARVs），alcohol abuse，toxins（e.g.aflatoxin），blood transfusion，or sexual contacts.
（1）Physical examination：
①Skin：spider naevi，telangiectases，palmar erythema，jaundice
②Abdomen：ascites，splenomegaly，enlarged or reduced liver size，liver nodules.
③General examination：Dupytren's contracture，gynecomastia，encephalopathy.
（2）Necessary examinations：(https://www.daowen.com)
①FBC：anemia，pancytopenia.
②Biochemical tests：LFT（transaminase↑，bilirubin↑），hyponatremia，hypoalbuminemia，hypogl-ycemia.
③Serology：HBSAg.
④Diagnostic puncture：ascites，hemorrhage，malignancy，Spontaneous Bacterial Peritonitis（SBP），PBC＞250/μL.
⑤Abdomen USS：ascites，splenomegaly，enlarged or reduced liver size，liver nodules，cirrhosis，hepatoma，periportal fibrosis.
⑥Rectal examination：fresh blood，melaena？→sings for esophageal or fundal varices.