Pancreas (C25)
In 2016, pancreatic cancer cases accounted for 1.61% of all cancer cases in Henan cancer registration areas with the crude incidence of 4.33/105,ASR for China 3.34/105 and ASR for World 3.33/105.The incidence in males was 4.73/105, and 3.90/105 in females.It was 1.37 times in males as high as that in females and it was 1.42 times in urban areas as that in rural areas.The crude mortality of pancreatic cancer in 2016 was 3.12/105, ASR for China was 2.36/105 and ASR for World 2.35/105.The mortality in males was 3.42/105, and 2.79/105 in females.The cumulative rates of incidence and mortality from 0 to 74 years old were 0.40% and 0.26%, respectively.(Table 5-8)
表5-8 河南省肿瘤登记地区胰腺恶性肿瘤发病与死亡
胰腺恶性肿瘤年龄别发病率和死亡率在0~44 岁年龄段处于较低水平，45 岁以后快速上升，在85+岁组达到高峰，男性高于女性。城乡和不同地区年龄别率的水平虽然有一定的差异，但总体趋势类同。（图5-8a ～图5-8f）
The age-specific incidence and mortality rates of pancreatic cancer were relatively low before 45 years old and increased dramatically since 45 years old, reaching the peak at the age group of 85+.Incidence and mortality rates in males were generally higher than those in females.Although the agespecific incidence and mortality rates varied in urban and rural areas, they showed similar curves.(Figure 5-8a~figure 5-8f)
图5-8a 河南省肿瘤登记地区胰腺恶性肿瘤年龄别发病率，2016
图5-8d 河南省肿瘤登记地区胰腺恶性肿瘤年龄别死亡率，2016
图5-8b 城市肿瘤登记地区胰腺恶性肿瘤年龄别发病率，2016
图5-8e 城市肿瘤登记地区胰腺恶性肿瘤年龄别死亡率，2016
图5-8c 农村肿瘤登记地区胰腺恶性肿瘤年龄别发病率，2016(https://www.daowen.com)
图5-8f 农村肿瘤登记地区胰腺恶性肿瘤年龄别死亡率，2016
在8 个城市肿瘤登记地区中，男性胰腺恶性肿瘤标化发病率最高的是洛阳市（8.20/10 万），其次是濮阳市华龙区和信阳市浉河区；女性发病率最高的是鹤壁市（6.58/10 万），其次是洛阳市和南阳市卧龙区。男性标化死亡率最高的是洛阳市（8.61/10 万），女性死亡率最高的是鹤壁市（5.37/10 万）。（图5-8g）
Among the 8 urban cancer registration areas,the ASR China incidence rate of pancreas cancer in males was the highest in Luoyang City (8.20/105),followed by Shihe District of Xinyang City.In females,it was the highest in Hebi City (6.58/105), followed by Luoyang City and Wolong District of Nanyang City.The highest ASR China mortality rate was in Luoyang City in males (8.61/105) and was in Hebi City in females (5.37/105 ).(Figure 5-8g)
图5-8g 城市肿瘤登记地区胰腺恶性肿瘤发病率与死亡率
在27 个农村肿瘤登记地区中，男性胰腺恶性肿瘤标化发病率最高的是济源市（7.92/10 万），其次是巩义市和信阳市固始县；女性发病率最高的是济源市（4.87/10 万），其次是信阳市罗山县和固始县。男性标化死亡率最高的是济源市（5.19/10 万），女性死亡率最高的是信阳市罗山县（4.91/10 万）。（图5-8h）
Among the 27 rural cancer registration areas,the ASR China incidence rate of pancreatic cancer in males was the highest in Jiyuan City (7.92/105),followed by Gongyi City and Gushi County of Xinyang City.For females, it was the highest in Jiyuan City(4.87/105), followed by Luoshan County and Gushi County of Xinyang City.The highest ASR China mortality rate was in Jiyuan City in males (5.19/105)and was in Luoshan County of Xinyang City in females (4.91/105 ).(Figure 5-8h)
图5-8h 农村肿瘤登记地区胰腺恶性肿瘤发病率与死亡率
2016 年肿瘤登记地区胰腺癌发病病例中有确切解剖学亚部位（C25.0-C25.4，C25.7，C25.8）信息的占53.1%，亚部位未特指（C25.9）的占46.9%。在有亚部位的胰腺癌病例中，发生在胰头（C25.0）的占61.1%，胰体（C25.1）的占14.8%，胰尾（C25.2）的占6.2%，胰管（C25.3）的占1.2%，内分泌（C25.4）的占15.0%，其他部位（C25.7）的占1.0%，胰腺交搭跨越（C25.8）的占0.7%。（图5-8i）
Among all the reported pancreatic cancer cases in 2016, 53.1% had specified subcategories(C25.0-C25.4, C25.7，C25.8) and the rest 46.9%had unspecified anatomic site (C25.9).The specified subcategories of pancreas cancer included the head of pancreas (C25.0) (61.1%), body (C25.1) (14.8%),tail (C25.2) (6.2%), pancreatic duct (C25.3) (1.2%),endocrine (C25.4) (15.0%), other parts (C25.7) (1.0%)and overlapping (C25.8) (0.7%).(Figure 5-8i)
图5-8i 河南省胰腺癌发病亚部位构成（%）