Bladder (C67)
In 2016, bladder cancer cases accounted for 1.22% of all cancer cases in Henan cancer registration areas with the crude incidence of 3.27/105,ASR for China 2.52/105 and ASR for World 2.48/105.The incidence in males was 4.93/105, and 1.51/105 in females.It was 3.72 times in males as high as that in females and it was 1.49 times in urban areas as that in rural areas.The crude mortality of bladder cancer in 2016 was 1.37/105, ASR for China was 0.99/105 and ASR for World 1.01/105.The mortality in males was 2.04/105, and 0.66/105 in females.The cumulative rates of incidence and mortality from 0 to 74 years old were 0.29% and 0.09%, respectively.(Table 5-18)
表5-18 河南省肿瘤登记地区膀胱恶性肿瘤发病与死亡
膀胱恶性肿瘤年龄别发病率和死亡率在0~44 岁年龄段处于较低水平，45 岁以后快速上升，在80~岁或85+岁组达到高峰，男性高于女性。城乡和不同地区年龄别率的水平虽然有一定的差异，但总体趋势类同。（图5-18a ～图5-18f）
The age-specific incidence and mortality rates of bladder cancer were relatively low before 44 years old and increased rapidly since 45 years old, reaching the peak at the age group of 80~ or 85+, respectively.Incidence rates in males was generally higher than those in females.The age-specific incidence and mortality rates varied in urban and rural areas with similar curves.(Figure 5-18a~figure5-18f)
图5-18a 河南省肿瘤登记地区膀胱恶性肿瘤年龄别发病率，2016
图5-18d 河南省肿瘤登记地区膀胱恶性肿瘤年龄别死亡率，2016
图5-18b 城市肿瘤登记地区膀胱恶性肿瘤年龄别发病率，2016
图5-18e 城市肿瘤登记地区膀胱恶性肿瘤年龄别死亡率，2016
图5-18c 农村肿瘤登记地区膀胱恶性肿瘤年龄别发病率，2016
图5-18f 农村肿瘤登记地区膀胱恶性肿瘤年龄别死亡率，2016(https://www.daowen.com)
在8 个城市肿瘤登记地区中，男性膀胱恶性肿瘤标化发病率最高的是洛阳市（13.86/10万），其次是濮阳市华龙区和南阳市卧龙区；女性发病率最高的是洛阳市（2.86/10 万），其次是南阳市卧龙区和三门峡市湖滨区。男性标化死亡率最高的是洛阳市（6.06/10 万），女性死亡率最高的是洛阳市（1.97/10 万）。（图5-18g）
Among the 8 urban cancer registration areas,the ASR China incidence rate of bladder cancer in males was the highest in Luoyang City (13.86/105),followed by Hualong District of Puyang City and Wolong District of Nanyang City.In females, it was the highest in Luoyang City (2.86/105), followed by Wolong District of Nanyang City and Hualong District of Puyang City.The highest ASR China mortality were in Luoyang City for both males (6.06/105) and females(1.97/105).(Figure 5-18g)
图5-18g 城市肿瘤登记地区膀胱恶性肿瘤发病率与死亡率
在27 个农村肿瘤登记地区中，男性膀胱恶性肿瘤标化发病率最高的是巩义市（10.94/10万），其次是洛阳市汝阳县和洛阳市新安县；女性发病率最高的是洛阳市孟津县（2.54/10 万），其次是巩义市和洛阳市偃师市。男性标化死亡率最高的是平顶山市鲁山县（3.97/10 万），女性死亡率最高的是商丘市睢县（2.21/10 万）。（图5-18h）
Among the 27 rural cancer registration areas, the ASR China incidence rate of bladder cancer in males was the highest in Gongyi City (10.94/105), followed by Ruyang County of Luoyang City and Xin'an County of Luoyang City.For females, it was the highest in Mengjin County of Luoyang City (2.54/105), followed by Gongyi City and Yanshi City of Luoyang City.The ASR China mortality was the highest in Lushan County of Pingdingshan City for males (3.97/105) and Sui County of Shangqiu City for females (2.21/105).(Figure 5-18h)
图5-18h 农村肿瘤登记地区膀胱恶性肿瘤发病率与死亡率
2016 年肿瘤登记地区膀胱恶性肿瘤发病病例中有确切解剖学亚部位（C67.0-C67.7，C67.8）信息的占26.6%，亚部位未特指（C67.9）的占73.4%。在有亚部位的膀胱癌病例中，发生在膀胱三角区（C67.0）的占31.0%，膀胱侧壁（C67.2）的占15.7%，膀胱顶（C67.1）的占13.7%，膀胱后壁（C67.4）的占11.8%，膀胱前壁（C67.3）的占10.2%，膀胱交搭跨越（C67.8）的占6.9%。膀胱颈（C67.5）的占5.9%，输尿管口（C67.6）的占1.9%，脐尿管（C67.7）的占1.2%。（图5-18i）
Among all the reported bladder cancer cases in 2016, 26.6% had specific anatomic site information(C67.0-C67.7，C67.8) and the rest 73.4% didn't have.The specific anatomic sites of kidney cancer included trigone (C67.0) (31.0%), dome (C67.1)(13.7%), lateral (C67.2) (15.7%), posterior (C67.4)(11.8%), anterior (C67.3) (10.2%),the overlapping part (C67.8) (6.9%) , bladder neck (C67.5) (5.9%),ureteric orifice (C67.6) (1.9%) and urachus (C67.7)(1.2%).(Figure 5-18i)
图5-18i 河南省膀胱恶性肿瘤发病亚部位构成(%)
2016 年肿瘤登记地区膀胱恶性肿瘤发病病例中有明确组织病理学分型的占51.2%，组织学类型未特指的占48.8%。在有组织病理学分型的膀胱癌病例中，移行细胞癌占37.3%，鳞状细胞癌占28.4%，腺癌占16.9%，其他类型的膀胱癌占17.3%。（图5-18j）
Among all cases, 51.2% had specific pathological diagnostic information and the rest 48.8% didn't have.Squamous cell carcinoma accounted for 28.4% of the cases with specific pathological diagnostic information, transitional cell carcinoma accounted for 37.3%, adenocarcinoma 16.9% and other pathological type 17.3%.(Figure 5-18j)
图5-18j 河南省膀胱恶性肿瘤发病形态学构成(%)