3.1 Ductal Carcinoma in Situ
The term：Clonal proliferation of malignant epithelial cells derived from terminal ductal lobular units anduninvasive basement membrane.
Clinical manifestation：
●Asymptomatic：Molybdenum target found calcification
●Touching a lump or mammography to find a mass/symmetry
●Nipple discharge
Population distribution characteristics：
●Age 40-60 years old susceptible disease
●Molybdenum target screening can improve detection rate：25%-33%of all screening cancers，5%of symptomatic cancers
Mammography：
●Calcification is most common：Accounting for 70%-80%of all ductal carcinoma in situ
☆Fine line or branch calcification：This performance is highly suggestive of ductal carcinoma in situ and is common in high-grade ductal carcinoma in situ
☆Polymorphic calcification：25%-40%for ductal carcinoma in situand this performance can be seen at any level
☆Unshaped calcification：20%is malignant；90%of ductal carcinoma in situ
●Calcification distribution：
The most common group distribution
Line or segment distribution：this phenomenon suggests ductal carcinoma in situ
●Tumor with calcification：clear edge
MR：(https://www.daowen.com)
●Morphological performance is more important than functionality
●Non-tumor reinforcement of line or segmental clusters
●Enhanced time signal strength curve changeable：slow inflow or platform type visible
Image inspection recommendation：
●Best image inspection method：Molybdenum target and MR
Case 1
Fig.（a-l）DR+MR Female，50 years old，with double breast pain for more than 3 years.Pathology：left breast ductal carcinoma in situ.
Case 2
Fig.（a-d）DR Female，43 years old，physical examination found a double breast mass in February.Pathology：left breast ductal carcinoma in situ.
Case 3
Fig.（a-n）DR+MR Female，34 years old，found nipple discharge for more than 10 days.Pathology：extensive ductal carcinoma in situ in the left breast.