3.2　Invasive Ductal Carcinoma

3.2　Invasive Ductal Carcinoma

The term：Invasive ductal carcinoma，non-special type，tumor cells break through the basement membrane；lack of myoepithelial cells

Clinical manifestation：

●Breast mass，with or without pain

●Abnormal nipple（effusion，shrink，eczema）

●Regional lymphadenopathy

Population distribution characteristics：

●The peak incidence is after 40 years old

●The disease is the most common type of invasive cancer and accounts for 40%-75%of invasive breast cancer

Mammography：

●Irregular/high-density lumps of marginal burrs，infiltrates or small lobes：31-43%with calcification

●Diffuse or localized trabecular thickening of the breast（edema），with or without skin thickening

●Focal asymmetry，Structural distortion

MR：

●T1W1：Multi-present signal，T2W1 fat suppression phase：Signal level is different，mostly equal or slightly lower signal(https://www.daowen.com)

●DWI signal increase，ADCreduce

●Hemodynamics：Early rapid and obvious reinforcement，latency is gradually or quickly cleared

Image inspection recommendation：

●Best image inspection method：

☆Screening：Mammography±DBT（Mammary digital tomosynthesis imaging）

☆High-risk groups need to be combined with breast MR screening

☆Initially examined age＜30 years old，pregnant or symptomatic lactating patients should choose ultrasound

Case 1

Fig.（a-c）DR，44 years old，found a left breast mass for one year.examination：left breast ductal carcinoma，part of invasive cancer，nipple involvement.

Case 2

Fig.（a-l）DR+MR 45 years old，found that the right breast mass with skin depression for half a year.examination：right breast invasive ductal carcinoma