2.1　Sample collection

Sample of the fungus O.sinensis(CCTCC AF 2017003)was from the fruiting body of the wild O.sinensis.Fresh specimens were purchased in a local market in Guoluo of Qinghai Province，China(Latitude 34.48°N，Longitude 100.23°E).Governmental permission is not required for O.sinensis purchases in local markets，and the collections of O.sinensis specimen sold by local farmers fall under the governmental regulations for traditional Chinese herbal products.All fresh O.sinensis specimens were washed thoroughly on site in running water with gentle brushing，soaked in 75%ethanol for 10min for surface sterilization and washed again 3 times with sterile water.These samples were snap-frozen in liquid nitrogen immediately after sampling，transported to our laboratory by using the solid carbon dioxide，and stored at—80℃until further use.The wild O.sinensis was preliminarily identified according to the morphological characteristics and several nuclear loci，including internal transcribed spacer region(ITS)，small and large 18S nuclear ribosomal RNA subunits(nrSSU，nr LSU)and translation elongation factor 1-alpha(TEF-1α).These four genes(GenBank accession number：MF403011，MF403012，MF403013，MF425658)all showed the highest homology to O.sinensis.(https://www.daowen.com)