2.3 Assessment of systemic anaphylactic symptoms
The extent of anaphylactic responses induced by ovalbumin or cattle albumin was evaluated on the basis of the occurrence of typical clinical symptoms of anaphylaxis，which were graded as follows：no symptom，—；nose rubbing and/o fur erection，±；weakness，dyspnea，coughing，sneezing，vomiting and/or wheezing，+；convulsion，cyanoses and/or collapse，++；death，+++.(https://www.daowen.com)