2.1　Reagents and antibodies

SAC，DADS，DTS，DATS and allyl sulfide(DAS)were purchased from LKT Laboratories(St Paul，USA).Leupeptin was purchased from Sigma-Aldrich(St Louis，USA).The Caspase 3 activity assay kit was purchased from Beyotime Biotechnology(Nanjing，China).Anti-LC3 polyclonal antibody for immunofluorescence staining and western blot analysis was obtained from Medical and Biological Laboratories(MBL，Nagoya，Japan).Anti-SQSTM1/p62 antibody was purchased from MBL.Antip70S6K and anti-phospho-p70S6K antibodies were purchased from Cell Signaling Technology(Beverly，USA).Anti-GAPDH antibody was purchased from YTHX Biotechnology Co.Ltd(Beijing，China).Anti-ATG5 antibody was obtained from Abcam(Cambridge，UK).Propidium iodide(PI)and Annexin V/Fluorescein isothiocyanate(FITC)for flow cytometry were purchased from Beyotime Biotechnology.Goat antimouse IgG and goat anti-rabbit antibodies were purchased from SouthernBiotech(Birmingham，USA).The Annexin V-FITC/PI Apoptosis Detection Kit was obtained from BD Biosciences(San Diego，USA).(https://www.daowen.com)