五、一般治疗

五、一般治疗

(一)治疗原则

目前尚无满意的疗法。

(二)治疗建议

可用皮质类固醇、氮芥(chlormethine)、环磷酰胺、长春新碱、氯喹、阿司匹林(aspirn)等治疗。亦可用ACTH、氮芥、盐酸氯化喹啉三联疗法。还可试用雷公藤(tripterygium)等。

参考文献

[1]Lesher J L Jr,Allen B S.Multicentric reticulohistiocytosis[J].Journal of the American Academy of Dermatology,1984,11(4):713-723.(https://www.daowen.com)

[2]Blanco J J R,Hernández F J B,Cerezo J G,et al.Multicentric reticulohistiocytosis.The long course of a rare disease[J].Scandinavian Journal of Rheumatology,2002,31(2):107-109.

[3]Gorman J D,Danning C,Schumacher H R,et al.Multicentric reticulohistiocytosis:Case report with immunohistochemical analysis and literature review[J].Arthritis&Rheumatism,2000,43(4):930-938.

[4]Islam A D,Naguwa S M,Cheema G S,et al.Multicentric reticulohistiocytosis:A rare yet challenging disease[J].Clinical Reviews in Allergy & Immunology,2013,45(2):281-289.

[5]Satoh M,Oyama N,Yamada H,et al.Treatment trial of multicentric reticulohistiocytosis with a combination of predonisolone,methotrexate and alendronate[J].The Journal of Dermatology,2008,35(3):168-171.

(郑晓姣 王志勇)