3.1 GA I protects MIN-6 cell's apoptosis under high glucose stress
High glucose toxicity has been shown in an animal model to contribute to development of insulin resistance，impaired insulin secretion，and pancreatic isletβ-cells withered(Biddinger& Kahn，2006).We observed that 33.3mmol/L glucose-induced apoptosis of MIN-6，while 5μg/mL GA I treatment decreased apoptosis of MIN-6 under the high glucose stress(Figure 1a，b).(https://www.daowen.com)