七、参考文献
[1]Bruce JP,Hui AB,Shi W,et al.Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma[J].Oncotarget,2015,6:4537-4550.
[2]Torre LA,Bray F,Siegel RL,et al.Global cancer statistics,2012[J].CA Cancer J Clin,2015,65:87-108.
[3]Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015[J].CA Cancer J Clin,2016,66:115-132.
[4]Chua ML,Wee JT,Hui EP,et al.Nasopharyngeal Carcinoma[J].Lancet.2016,387:1012-1024.
[5]Cao SM,Simons MJ,Qian CN.The prevalence and prevention of nasopharyngeal carcinoma in China[J].Chinese Journal of Cancer Research,2011,30:114-119.
[6]Sun Y,Li WF,Chen NY,et al.Induction chemotherapy plus concurrent chemoradiotherapy versusconcurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma:a phase 3,multicentre,randomised controlled trial[J].Lancet Oncol,2016,17:1509-1520.
[7]Wang M,Tian H,Li G,Ge T,Liu Y,Cui J,Han F.Significant benefits of adding neoadjuvant chemotherapy before concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma:a meta-analysis of randomized controlled trials[J].Oncotarget,2016,7:48375-48390.
[8]DeNittis AS,Liu L,Rosenthal DI,et al.Nasopharyngeal carcinoma treated with external radiotherapy,brachytherapy,and concurrent/adjuvant chemotherapy[J].Am J Clin Oncol,2002,25(1):93.
[9]Zhou BB,Elledge SJ.The DNA damage response:putting check-points in perspective[J].Nature,2000,408(6811):433-439.
[10]Gerweck LE,Vijayappa S,Kurimasa A,et al.Tumor cell radiosensitivity is a major determinant of tumor response to radiation[J].Cancer Res.2006,66:8352-8355.
[11]Vaupel P,Hoeckel M.Predictive power of the tumor oxygenation status[J].Adv Exp Med Biol,1999,471:533-539.
[12]Karar J,Maity A.Modulating the tumor microenvironment to increase radiation responsiveness[J].Cancer Biol Ther,2009,8(21):1994-2001.(https://www.daowen.com)
[13]Koch CJ,Kruuv J,Frey HE.Variation in radiation response of mammalian cells as a function of oxygen tension[J].Radiat Res,1973,53:33-42.
[14]Spannuth W.A.,Sood A.K.& Coleman R.L.Angiogenesis as a strategic target for ovarian cancer therapy[J].Nat Clin Pract Onco,2008,15:194-204.
[15]Guang-Wu H,Sunagawa M,Jie-En L,et al.The relationship between microvessel density,the expression of vascular endothelial growth factor(VEGF),and the extension of nasopharyngeal carcinoma[J].Laryngoscope,2000,110(12):2066-2069.
[16]Hui EP,Chan AT,Pezzella F,et al.Coexpression of hypoxia-inducible factors 1alpha and 2alpha,carbonic anhydraseⅨ,and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival[J].Clin Cancer Res,2002,8(8):2595-2604.
[17]Li YH,Hu CF,Shao Q,et al.Elevated expressions of survivin and VEGF protein are strong independent predictors of survival in advanced nasopharyngeal carcinoma[J].J Transl Med,2008,6:1.
[18]Sha D,He YJ.Expression and clinical significance of VEGF and its receptors Flt-1 and KDR in nasopharyngeal carcinoma[J].Ai Zheng,2006,25(2):229-234.
[19]Jain RK.Normalization of tumor vasculature:an emerging Concept in antiangiogenictherapy[J].Science,2005,307(5706):58-62.
[20]Teicher BA,Holden SA,Ara G,et al.Influence of all antiangiogenic treatment on 9L gliosarcoma,oxygenation and response to cytotoxic therapy[J].Int J Cancer,1995,61(5):732.
[21]Zhou J,Wang L,Xu X,et al.Antitumor activity of Endostar combined with radiation against humannasopharyngeal carcinoma in mouse xenograft models[J].Oncol Lett,2012,4(5):976-980.
[22]Peng QX,Han YW,Zhang YL,et al.Apatinib inhibits VEGFR-2 and angiogenesis in an in vivo murine model of nasopharyngeal carcinoma[J].Oncotarget,2017,8(32):52813-52822.
(杨 峥)