部分研究方向
1.HIV患者中HPV、EBV等病毒易感性在口腔病损(口腔毛状白斑、口腔疣、Kaposi肉瘤等)发病机制中的作用。治疗HIV相关的口腔黏膜病损的药物研究。
2.精神心理因素在灼口综合征发病机制中的作用。精神治疗药物在治疗灼口综合征的机制。
3.SS相关的HLA异常表达的免疫遗传学研究。SS免疫相关的差异蛋白组学研究。
4.BD的非特异血管炎的免疫形成机制及治疗研究。
5.莱特尔综合征发病机制研究,沙眼衣原体、志贺菌、沙门菌等病原体抗原的免疫学发病机制。
6.副结核分枝杆菌、抗酿酒酵母等条件致病菌在克罗恩病发病机制中的作用。
7.梅-罗综合征、Ascher综合征和克罗恩病等唇部肉芽肿的发病因素及其相互联系的研究。
8.Goltz-Gorlin综合征的PORCN基因突变研究,PORCN基因靶向Wnt信号通路的机制研究,以及Wnt信号通路异常导致胚胎畸形的机制。
9.普杰综合征、色素失禁综合征等遗传性色素沉着综合征的基因突变的遗传学研究。
10.LKB1基因突变在普杰综合征的黑色素沉着病损形成机制研究。
11.Laugier-Hunziker-Baran综合征的临床表现与鉴别诊断。
12.Albright综合征发病机制研究。
13.干燥综合征的口腔微生物群分析。
14.Wolfram综合征患者味觉和嗅觉功能的改变。
15.儿童prader-willi综合征的口腔表现。
16.Van der Woude综合征家族基因分析。
17.以口腔溃疡起病的sweet综合征的临床表现。
18.RAS信号通路相关综合征的口腔颅颌面部特征。
19.Behçet's综合征的研究进展。
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(王文梅 黄帆 段宁)