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Study on the Active Components Accumulation in Cordceps militaris Throngh Femention Process
Luo Wei1,2 Liu Dong-bo1,2 Wu Zheng-wu1,2 Xia Zhi-lan1,2 Xie Hong-qi1,3
1.College of Horticulture and Landscape,Hunan Agricultural University,Changsha 410128,China
2.State Administration of Traditional Chinese Medicine Sub-health Intervention Technology Laboratory Hunan Agricultural University,Changsha 410128,China
3.Key Laboratory for Crop Germplasm Innovation and Utilization of Hunan Province,Changsha 410128,China
Abstract:The dynamic variation of the accumulation of biomass,Cordyceps polysaccharides,cordycepic acid and cordycepin were compared through fermentation process.The results showed that 70% of Cordyceps polysaccharide,Cordyceps acid and cordycepin was distributed in the fermentation broth.The optimum fermentation period was 12d by considering these three products.The results of 10 L fermentation tank submerged culture test showed that the biomass reached 24.5 mg/mL,which increased 19.86%compared with shaking flask culture,while the Cordyceps acid,CP,cordycepin content were 7.43mg/mL,2.82mg/m L,90.73μg/mL respectively,which increased 8.3%,13.7% and 15.6%compared with shaking flask culture.
Keywords:Cordyceps militaris,cordycepic acid,cordycepin,Cordyceps polysaccharide