3.2 TGSO reduced the percentages of apoptotic cells from 43.80%to 15.44%
To evaluate the effect of TGSO,the apoptotic rate of RINm5F cell exposure to high glucose with/without TGSO were investigated.After exposure to high glucose for 48h,apoptotic rate of model group was significantly increased to 43.80%,which was 27.8-fold higher than that of the control.However,in the condition of co-culture with 100μg/mL TGSO,the percentages of apoptotic cells were reduced to 15.44%(Figure 1).
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Figure 1 Effects of TGSO on Rin-m5F Cells Apoptosis Induced by High Glucose.
Data represent mean±S.D(n=3 for each group).The values are statistically significant and presented as follows:**p<0.01 vs.control group;# #p<0.01 vs.model group.