3.3 TGSO protectedβ-cells from insulin impairment induced by high glucose
As insulin release is one of the variables to assess high glucose-induced damage and protection afforded by TGSO,insulin concentrations of supernatant were decreased significantly after exposure to high glucose.TGSO recovered insulin secretion damage induced by high glucose to the comparable level of the control in Rin-m5F cells(Figure 2).
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Figure 2 Effects of TGSO on Insulin Secretion in Rin-m5F Cells Induced by High Glucose.
Data represent mean±S.D(n=3 for each group).The values are statistically significant and presented as follows:*p<0.05 vs.control group;#p<0.05 vs.model group.