参考文献
[1] Rana S，Lemoine E，Granger J P，et al.Preeclampsia：pathophysiology，challenges，and perspectives[J].Circ Res，2019，124（7）：1094-1112.
[2] Chaiworapongsa T，Chaemsaithong P，Yeo L，et al.Pre-eclampsia part 1：current understanding of its pathophysiology[J].Nat Rev Nephrol，2014，10（8）：466-480.
[3] Ahmed A，Rezai H，Broadway-Stringer S.Evidence-based revised view of the pathophysiology of preeclampsia[J].Adv Exp Med Biol，2017，956：355-374.
[4] Ives C W，Sinkey R，Rajapreyar I，et al.Preeclampsia-pathophysiology and clinical presentations：JACC state-of-the-art review[J].J Am Coll Cardiol，2020，76（14）：1690-1702.
[5] Miller E C，Vollbracht S.Neurology of preeclampsia and related disorders：an update in neuro-obstetrics[J].Curr Pain Headache Rep，2021，25（6）：40.
[6] 毕光辉，曲星华，崔素梅.妊娠卒中33例临床分析[J].齐鲁医学杂志，2006，21（6）：527-528.
[7] Wertaschnigg D，Wang R，Reddy M，et al.Treatment of severe hypertension during pregnancy：we still do not know what the best option is[J].Hypertens Pregnancy，2020，39（1）：25-32.
[8] Harrow B R，Sloane J A，Salhanick L.Etiology of the hydronephrosis of pregnancy[J].Surg Gynecol Obstet，1964，119：1042-1048.
[9] Rasmussen P E，Nielsen F R.Hydronephrosis during pregnancy：a literature survey[J].Eur J Obstet Gynecol Reprod Biol，1988，27（3）：249-259.
[10] Wadasinghe S U，Metcalf L，Metcalf P，et al.Maternal physiologic renal pelvis dilatation in pregnancy：sonographic reference data[J].J Ultrasound Med，2016，35（12）：2659-2664.
[11] Faúndes A，Brícola-Filho M，Pinto e Silva J L.Dilatation of the urinary tract during pregnancy：proposal of a curve of maximal caliceal diameter by gestational age[J].Am J Obstet Gynecol，1998，178（5）：1082-1086.
[12] Leyendecker J R，Gorengaut V，Brown J J.MR imaging of maternal diseases of the abdomen and pelvis during pregnancy and the immediate postpartum period[J].Radiographics，2004，24（5）：1301-1316.
[13] Davison J M.The kidney in pregnancy：a review[J].J R Soc Med，1983，76（6）：485-501.
[14] Cheung K L，Lafayette R A.Renal physiology of pregnancy[J].Adv Chronic Kidney Dis，2013，20（3）：209-214.
[15] Yu T，Khraibi A A.Natriuretic response to direct renal interstitial volume expansion（DRIVE）in pregnant rats[J].Am J Hypertens，2005，18（6）：851-857.
[16] Maesaka J K，Fishbane S.Regulation of renal urate excretion：a critical review[J].Am J Kidney Dis，1998，32（6）：917-933.
[17] Fathallah-Shaykh S A，Cramer M T.Uric acid and the kidney[J].Pediatr Nephrol，2014，29（6）：999-1008.
[18] Hwu C M，Lin K H.Uric acid and the development of hypertension[J].Med Sci Monit，2010，16（10）：Ra224-Ra230.
[19] Bainbridge S A，Roberts J M.Uric acid as a pathogenic factor in preeclampsia[J].Placenta，2008，29（Suppl A）：S67-S72.
[20] Keller F，Griesshammer M，Häussler U，et al.Pregnancy and renal failure：the case for application of dosage guidelines[J].Drugs，2001，61（13）：1901-1920.
[21] Helal I，Fick-Brosnahan G M，Reed-Gitomer B，et al.Glomerular hyperfiltration：definitions，mechanisms and clinical implications[J].Nat Rev Nephrol，2012，8（5）：293-300.
[22] Barrett P M，McCarthy F P，Kublickiene K，et al.Adverse pregnancy outcomes and long-term maternal kidney disease：a systematic review and meta-analysis[J].JAMA Netw Open，2020，3（2）：e1920964.
[23] Koratala A，Bhattacharya D，Kazory A.Chronic kidney disease in pregnancy[J].South Med J，2017，110（9）：578-585.
[24] Oishi M，Iino K，Tanaka K，et al.Hypertensive disorders of pregnancy increase the risk for chronic kidney disease：a population-based retrospective study[J].Clin Exp Hypertens，2017，39（4）：361-365.
[25] Basgul A，Kavak Z N，Sezen D，et al.A rare case of early onset nephrotic syndrome in pregnancy[J].Clin Exp Obstet Gynecol，2006，33（2）：127-128.
[26] De Castro I，Easterling T R，Bansal N，et al.Nephrotic syndrome in pregnancy poses risks with both maternal and fetal complications[J].Kidney Int，2017，91（6）：1464-1472.
[27] Hayashi S，Ohashi N，Goto D，et al.A case of hypertensive disorders of pregnancy that developed at 9 weeks of gestation[J].CEN Case Rep，2021，10（4）：476-482.
[28] Siligato R，Gembillo G，Cernaro V，et al.Maternal and fetal outcomes of pregnancy in nephrotic syndrome due to primary glomerulonephritis[J].Front Med（Lausanne），2020，7：563094.
[29] Kia L，Rinella M E.Interpretation and management of hepatic abnormalities in pregnancy[J].Clin Gastroenterol Hepatol，2013，11（11）：1392-1398.
[30] Chazouillères O，Bacq Y.The liver and pregnancy[J].Gastroenterol Clin Biol，2004，28（5 Suppl）：D84-D91.
[31] Gonzalez-Brown V，Frey H A.The hepatobiliary system：an overview of normal function and diagnostic testing in pregnancy[J].Clin Obstet Gynecol，2020，63（1）：122-133.
[32] Denhez B，Wang L，Moreau J，et al.Interlaboratory bias of albuminuria and proteinuria in hypertensive pregnancy[J].Clin Biochem，2021，87：13-18.
[33] Devarbhavi H，Rao P，Patil M，et al.Characteristics of ascites in patients with pregnancy-specific liver diseases[J].Clin Gastroenterol Hepatol，2012，10（5）：559-562.
[34] Hamoud A R，Weaver L，Stec D E，et al.Bilirubin in the Liver-Gut Signaling Axis[J].Trends Endocrinol Metab，2018，29（3）：140-150.
[35] Duraiswamy S，Sheffield J S，McIntire D，et al.Updated etiology and significance of elevated bilirubin during pregnancy：changes parallel shift in demographics and vaccination status[J].Dig Dis Sci，2017，62（2）：517-525.
[36] Cho G J，Kim H Y，Park J H，et al.Prepregnancy liver enzyme levels and risk of preeclampsia in a subsequent pregnancy：a population-based cohort study[J].Liver Int，2018，38（5）：949-954.
[37] Rajagambeeram R，Abu Raghavan S，Ghosh S，et al.Diagnostic utility of heat stable alkaline phosphatase in hypertensive disorders of pregnancy[J].J Clin Diagn Res，2014，8（11）：CC10-3.
[38] Wilkof-Segev R，Hallak M，Gabbay-Benziv R.Extremely high levels of alkaline phosphatase and pregnancy outcome：case series and review of the literature[J].J Perinat Med，2021，49（2）：191-194.
[39] Shaheen G，Sajid S，Jahan S.Evaluation of coagulation factors and serum ferritin in preeclamptic Pakistani women[J].J Pak Med Assoc，2020，70（11）：2048-2050.
[40] Pinheiro M B，Gomes K B，Dusse L M.Fibrinolytic system in preeclampsia[J].Clin Chim Acta，2013，416：67-71.
[41] Ganzevoort W，Rep A，De Vries J I，et al.Relationship between thrombophilic disorders and type of severe early-onset hypertensive disorder of pregnancy[J].Hypertens Pregnancy，2007，26（4）：433-445.
[42] Vigil-De Gracia P.HELLP syndrome[J].Ginecol Obstet Mex，2015，83（1）：48-57.
[43] Ganzevoort W，Rep A，Bonsel G J，et al.Plasma volume and blood pressure regulation in hypertensive pregnancy[J].J Hypertens，2004，22（7）：1235-1242.
[44] de Haas S，Ghossein-Doha C，van Kuijk S M，et al.Physiological adaptation of maternal plasma volume during pregnancy：a systematic review and meta-analysis[J].Ultrasound Obstet Gynecol，2017，49（2）：177-187.
[45] Eslick R，Mc Lintock C.Managing ITP and thrombocytopenia in pregnancy[J].Platelets，2020，31（3）：300-306.
[46] Tsikouras P，Niesigk B，von Tempelhoff G F，et al.Blood rheology during normal pregnancy[J].Clin Hemorheol Microcirc，2018，69（1-2）：101-114.
[47] Ren K，Wei Y，Qiao R，et al.Changes in coagulation during twin pregnancies[J].Clin Appl Thromb Hemost，2020，26：1076029620983898.
[48] Wheeler A P，Hemingway C，Gailani D.The clinical management of factorⅪdeficiency in pregnant women[J].Expert Rev Hematol，2020，13（7）：719-729.
[49] Sato I，Nakayama T，Maruyama A，et al.Study of association between hypertensive disorders of pregnancy and the human coagulation factorⅪgene[J].Hypertens Pregnancy，2006，25（1）：21-31.
[50] Sayin M，Varol F G，Sayin N C.Evaluation of natural coagulation inhibitor levels in various hypertensive states of pregnancy[J].Eur J Obstet Gynecol Reprod Biol，2005，123（2）：183-187.
[51] Alvarez-Alvarez B，Martell-Claros N，Abad-Cardiel M，et al.Hypertensive disorders during pregnancy：cardiovascular long-term outcomes[J].Hipertens Riesgo Vasc，2017，34（2）：85-92.
[52] Ramlakhan K P，Johnson M R，Roos-Hesselink J W.Pregnancy and cardiovascular disease[J].Nat Rev Cardiol，2020，17（11）：718-731.
[53] Shimizu I，Minamino T.Physiological and pathological cardiac hypertrophy[J].J Mol Cell Cardiol，2016，97：245-262.
[54] Gibb A A，Hill B G.Metabolic coordination of physiological and pathological cardiac remodeling[J].Circ Res，2018，123（1）：107-128.
[55] Honigberg M C，Riise H K R，Daltveit A K，et al.Heart failure in women with hypertensive disorders of pregnancy：insights from the cardiovascular disease in norway project[J].Hypertension，2020，76（5）：1506-1513.
[56] Malek A M，Wilson D A，Turan T N，et al.Incident heart failure within the first and fifth year after delivery among women with hypertensive disorders of pregnancy and prepregnancy hypertension in a diverse population[J].J Am Heart Assoc，2021，10（17）：e021616.
[57] Balgobin C A，Zhang X，Lima F V，et al.Risk factors and timing of acute myocardial infarction associated with pregnancy：insights from the national inpatient sample[J].J Am Heart Assoc，2020，9（21）：e016623.
[58] Bauersachs J，König T，van der Meer P，et al.Pathophysiology，diagnosis and management of peripartum cardiomyopathy：a position statement from the heart failure association of the european society of cardiology study group on peripartum cardiomyopathy[J].Eur J Heart Fail，2019，21（7）：827-843.
[59] Stuart J J，Tanz L J，Cook N R，et al.Hypertensive disorders of pregnancy and 10-Year cardiovascular risk prediction[J].J Am Coll Cardiol，2018，72（11）：1252-1263.
[60] Benschop L，Duvekot J J，Roeters van Lennep J E.Future risk of cardiovascular disease risk factors and events in women after a hypertensive disorder of pregnancy[J].Heart，2019，105（16）：1273-1278.
[61] Grieger J A，Bianco-Miotto T，Grzeskowiak L E，et al.Metabolic syndrome in pregnancy and risk for adverse pregnancy outcomes：a prospective cohort of nulliparous women[J].PLoS Med，2018，15（12）：e1002710.
[62] Mohsenzadeh-Ledari F，Taghizadeh Z，Motaghi Z，et al.Appropriate interventions for pregnant women with indicators of metabolic syndrome on pregnancy outcomes：a systematic review[J].Int J Prev Med，2019，10：2.
[63] Boss A L，Chamley L W，James J L.Placental formation in early pregnancy：how is the centre of the placenta made？[J].Hum Reprod Update，2018，24（6）：750-760.
[64] Knöfler M，Haider S，Saleh L，et al.Human placenta and trophoblast development：key molecular mechanisms and model systems[J].Cell Mol Life Sci，2019，76（18）：3479-3496.
[65] Proctor L K，Kfouri J，Hiersch L，et al.Association between hypertensive disorders and fetal growth restriction in twin compared with singleton gestations[J].Am J Obstet Gynecol，2019，221（3）：251.e1-251.e8.
[66] Fajersztajn L，Veras M M.Hypoxia：from placental development to fetal programming[J].Birth Defects Res，2017，109（17）：1377-1385.
[67] Habek D，Habek J C，Jugovic′D，et al.Intrauterine hypoxia and sudden infant death syndrome[J].Acta Med Croatica，2002，56（3）：109-118.
[68] Thompson L P，Turan S，Aberdeen G W.Sex differences and the effects of intrauterine hypoxia on growth and in vivo heart function of fetal guinea pigs[J].Am J Physiol Regul Integr Comp Physiol，2020，319（3）：R243-R254.
[69] Naruse K，Shigemi D，Hashiguchi M，et al.Placental abruption in each hypertensive disorders of pregnancy phenotype：a retrospective cohort study using a national inpatient database in Japan[J].Hypertens Res，2021，44（2）：232-238.
[70] Lahti-Pulkkinen M，Girchenko P，Tuovinen S，et al.Maternal hypertensive pregnancy disorders and mental disorders in children[J].Hypertension，2020，75（6）：1429-1438.