五、治疗

五、治疗

(一)一般治疗

1.多学科联合治疗,手术恢复受累组织器官的正常形态及功能。

2.及时进行康复训练。

(二)口腔颌面部异常相关的治疗建议

1.早期外科手术治疗恢复患者的腭部形态与功能。

2.颌骨发育异常根据严重程度制定相应治疗方案,必要时行正畸-正颌手术联合治疗。

3.牙齿缺失患者,牙齿缺失数目较少时,应注意早期缺失牙的间隙管理,缺失牙齿数目较多时,可义齿型间隙保持,以保证患儿正常的咀嚼功能,待成年后可选择行种植修复或其他修复方式修复缺失牙。(https://www.daowen.com)

参考文献

[1]Zaytoun G M,Harboyan G,Kabalan W.The oto-palato-digital syndrome:Variable clinical expressions[J].Otolaryngology—Head and Neck Surgery,2002,126(2):129-140.

[2]Kira-Koizumi T,Mitsukawa N,Morishita T,et al.Clinical experience of treatment of facial malformations in oto-palato-digital syndrome:A familial patient[J].The Journal of Craniofacial Surgery,2017,28(4):1068-1070.

[3]Kozlowski K,Turner G,ScougallJ,et al.Oto-Palato-Digital syndrome with severe X-ray changes in two half brothers[J].Pediatric Radiology,1977,6(2):97-102.

[4]Kaissi A A,Kraschl R,Kaulfersch W,et al.Extended phenotypes in a boy and his mother with otopalato-digital-syndrome type Ⅱ[J].Clinical Case Reports,2015,3(9):762-766.

[5]Gall J C Jr,Stem A M,Poznanski A K,et al.Oto-palato-digital syndrome:Comparison of clinical and radiographic manifestations in males and females[J].American Journal of Human Genetics,1972,24(1):24-36.

(邢向辉 邱德春)