五、治疗
对症治疗,牙齿发育不良的行牙周维护,义齿修复,白内障可行手术或药物治疗。
参考文献
[1]Oshima J,Sidorova J M,Monnat R J Jr.Werner syndrome:Clinical features,pathogenesis and potential therapeutic interventions[J].Ageing Research Reviews,2017,33:105-114.
[2]Lauper J M,Krause A,Vaughan T L,et al.Spectrum and risk of neoplasia in Werner syndrome:A systematic review[J].PLoS One,2013,8(4):e59709.
[3]Oshima J,Hisama F M.Search and insights into novel genetic alterations leading to classical and atypical Werner syndrome[J].Gerontology,2014,60(3):239-246.
[4]Muftuoglu M,Oshima J,Kobbe C,et al.The clinical characteristics of Werner syndrome:Molecular and biochemical diagnosis[J].Human Genetics,2008,124(4):369-377.(https://www.daowen.com)
[5]林丽蓉.医学综合征大全[M].北京:中国科学技术出版社,1994.
[6]任军,刘晓坤,李新生,等.伴神经性耳聋的Werner综合征1例国内首报[J].中国皮肤性病学杂志,2012,26(1):1-5.
[7]曹彦飞,赵宏敏,王勇,等罕见病Werner综合征一例报告[J].临床误诊误治,2012,25(4):23-24.
[8]陈志强,后藤,真.Werner综合征[J].国外医学(皮肤性病学分册),1999(5):270-273.
[9]王泽华,李洪宇,曲静,等.人类早衰症的发病机制及干预方法[J].生物化学与生物物理进展,2018,45(9):926-934.
(蒋红柳 王文梅)