2.4 小结
FIGS 在CRC 的微创外科治疗领域具有广阔的应用前景，但其临床价值仍需更多更有说服力的循证医学证据支持。另外，相关应用规范和指南也亟待制订，以更好地指导结直肠外科医师工作。
（蔡正昊、冯波）
参考文献
[1]ABU GAZALA M,WEXNER S D.Re-appraisal and consideration of minimally invasive surgery in colorectal cancer[J].Gastroenterol Rep (Oxf),2017,5(1):1-10.
[2]KOCH M,NTZIACHRISTOS V.Advancing Surgical Vision with Fluorescence Imaging[J].Annu Rev Med,2016,67:153-164.
[3]NAMIKAWA T,SATO T,HANAZAKI K.Recent advances in near-infrared fluorescence-guided imaging surgery using indocyanine green[J].Surg Today,2015,45(12):1467-1474.
[4]BENYA R,QUINTANA J,BRUNDAGE B.Adverse reactions to indocyanine green: a case report and a review of the literature[J].Cathet Cardiovasc Diagn,1989,17:231-233.
[5]DORVAL P,MANGERET N,GUILLERMET S,et al.A palm-sized high-sensitivity near-infrared fluorescence imager for laparotomy surgery[J].Phys Med,2016,32(1):218-225.
[6]GROENLUND J H,TELINIUS N,SKOV S N,et al.A validation study of nearinfrared fluorescence imaging of lymphatic vessels in humans[J].Lymph Res Biol,2017,15(3):227-234.(https://www.daowen.com)
[7]LIBERALE G,BOHLOK A,BORMANS A,et al.Indocyanine green fluorescence imaging for sentinel lymph node detection in colorectal cancer: A systematic review[J].Eur J Surg Oncol,2018,44(9):1301-1306.
[8]KARLICZEK A,HARLAAR N,ZEEBREGTS C,et al.Surgeons lack predictive accuracy for anastomotic leakage in gastrointestinal surgery[J].Int J Colorectal Dis,2009,24(5):569-576.
[9]VAN DEN BOS J,AL-TAHER M,SCHOLS R M,et al.Near-Infrared Fluorescence Imaging for Real-Time Intraoperative Guidance in Anastomotic Colorectal Surgery: A Systematic Review of Literature[J].J Laparoendosc Adv Surg Tech A,2018,28(2):157-167.
[10]OGINO T,TAKEMASA I,HORITSUGI G,et al.Preoperative evaluation of venous anatomy in laparoscopic complete mesocolic excision for right colon cancer[J].Annals of surgical oncology,2014,21 Suppl 3:S429-435.DOI: 10.1245/s10434-014-3572-2.
[11]MAEDA H,WU J,SAWA T,et al.Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review[J].J Control Release,2000,65:271-284.
[12]LIBERALE G,BOURGEOIS P,LARSIMONT D,et al.Indocyanine green fluorescence-guided surgery after IV injection in metastatic colorectal cancer: A systematic review[J].Eur J Surg Oncol,2017,43(9):1656-1667.
[13]ZHANG R R,SCHROEDER A B,GRUDZINSKI J J,et al.Beyond the margins: real-time detection of cancer using targeted fluorophores[J].Nat Rev Clin Oncol,2017,14:347-364.
[14]HENTZEN J E K R,DE JONGH S J,HEMMER P H J,et al.Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: A narrative review[J].J Surg Oncol,2018,118(2):332-343.