3.3 Ginsenosides Inhibited High Glucose/Cytokines-...

更新于 2026年10月13日 版权声明
3.3 Ginsenosides Inhibited High Glucose/Cytokines-Induced iNOS Expression and Consequent NO Production

As shown in Figure 3,the relative expression levels of i NOS and NO production induced by high glucose were increased to 2.14 and 2.05 fold respectively,compared to control group.The two values were greatly reduced under treatment of ginsenosides.Moreover,similar result was observed in the cytokines-induced apoptotic cells.

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Figure 3 Effects of Ginsenosides on NO Production and iNOS Gene Expression in Rin-m5F Cells Induced by High Glucose/Cytokines

A and C,Rin-m5F cells were induced by high glucose and treated with or without ginsenosides;B and D,cells were induced by cytokines and treated with or without ginsenosides.A and Bshowed concentration of NO,and Cand D showed i NOS mRNA expressions.Data are shown as mean±S.E.M.of 3 independent experiments.
**p<0.01 vs.control group;#p<0.05,##p<0.01 vs.high glucose/cytokine group.

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