Application and Observation of Docetaxel 多西他赛的使用...
[Glossary]
docetaxel 多西他赛
chemotherapy 化疗
metastatic 转移性的
bone marrow 骨髓
gastrointestinal 胃肠道的
neurotoxicity 神经毒性
cardiovascular 心血管的
hypotension 低血压
itchiness 瘙痒
aseptic 无菌的
[Scenario]
护士1：吴教员，今天3床曾阿姨静滴多西他赛，我巡视的时候她询问了我这个药物的相关知识，我不是很清楚，您能给我讲讲吗？我想一会去给患者讲解。
N1：Teacher Wu，Ms.Zeng in bed 3 was treated with docetaxel intravenously.Today she asked me about this medicine when I visited her.I don't know a lot.Could you please tell me about it？I would like to explain it to the patient a moment later.
护士2：小芳，你是实习同学，对这个药物不了解很正常。3床阿姨我给她讲过一次了，可能她忘了，又询问你，一会我们一起再给患者做一次药物宣教。
N2：Xiao Fang，no worries.I understand that you do not know about this drug as you are an intern.The patient may have forgotten the instruction I gave toher before.We can do that again together.
护士1：好的。
N1：All right.
护士2：这是一个化疗药物，主要适用于以顺铂为主的化疗失败的晚期及转移性非小细胞肺癌或转移性乳腺癌的患者。用法为静脉滴注。这个药用之前需要服用糖皮质激素3天，以防出现过敏反应和体液潴留。
N2：This chemotherapy drug is mainly used for patients with advanced or metastatic non-small cell lung carcinoma and metastatic breast cancers that have failed to respond to cisplatin.It is administered via intravenous drip.The patient needs to receive corticosteroids for 3 days before taking docetaxel in order to prevent allergies and fluid retention.
护士1：不良反应有哪些？
N1：What are the side effects？
护士2：不良反应有：过敏反应、体液潴留、骨髓抑制、神经毒性反应、胃肠道反应、心血管副反应、皮肤反应等，严重者有低血压与支气管痉挛，需中断治疗。而皮肤反应主要表现为红斑，常见于手足，有时伴有瘙痒。
N2：The side effects include allergic reactions，fluid retention，bone marrow suppression，neurotoxicity，gastrointestinal reactions，cardiovascular adverse reactions，skin reactions or hypotension and bronchial spasm in severe cases.If any of these happen，we need to stop the treatment.The allergic skin reaction includes rash and itchiness commonly found in the hands and feet.
护士1：不良反应真多，我有点记不住了。
N1：It has so many adverse reactions that I cannotmemorize all of them.(https://www.daowen.com)
护士2：你可以这样记忆，如皮肤的反应、呼吸系统的、消化系统的、循环系统的等。
N2：You can memorize them according to tissue systems，such as skin reactions，respiratory system，digestive system，circulatory system，and so on.
护士1：这样好像也没有那么难了。
N1：Oh，it doesn't seem so difficult now.
护士2：我们要重点注意以下几点：当医生要使用这个药物时要查看医生是否开激素，激素会增加体液潴留的发生，要随时观察患者的体重变化；在滴注药物前，要做到现配现用；静滴几分钟后可能发生过敏反应，应注意观察患者的生命体征变化，准备好相应的急救设施；我们还要做好手卫生，做到无菌操作。
N2：We have to pay particular attention to several things：we need to check if the doctor has prescribed corticosteroid before the treatment.As corticosteroid can increase the morbidity of body fluid retention，we need to observe the patient's weight changes during the treatment.The drug should be prepared few minutes right before using.Remember to monitor the allergic reactions and vital signs during the administration，and have plans to deal with the side effects when it is needed.Also，we have to keep our hands clean and follow aseptic operation protocols.
护士1：我知道了。
N1：OK，I see.
护士2：其实还有很多地方需要我们注意，比如说做好患者的心理护理，这个也非常重要。
N2：In fact，there are a lot of other things we must payattention to，for example，the patient's psychological care.
护士1：教员，我记住了，我会好好学习的。
N1：I will keep these in mind and study hard later.
护士2：很好。
N2：Very good.
[Phrases]
intern 实习生
breast cancer 乳腺癌
in order to 为了
fluid retention 体液潴留
adverse reaction 不良反应
allergic reaction 过敏反应
bronchial spasm 支气管痉挛
respiratory system 呼吸系统
digestive system 消化系统
circulatory system 循环系统