3.4 Case Report:MERS CoV Infection in Renal Transp...
A 44-year-old male，who underwent a live-related renal transplant on September 13，2004 due to hypertensive nephrosclerosis，presented to the emergency department on March 30，2014，complaining of generalized fatigue of a 3-day duration.This was followed by a sore throat and shortness of breath that started 1 day prior to presentation.He denied cough，fever，diarrhea，abdominal pain or vomiting.There was no history of contact with similarly ill or febrile patients.On admission，he required 5-10 L/min of oxygen through facemask to maintain an oxygen saturation of 90%.Moreover，he had oliguria.
His laboratory testing revealed a white blood count of 2.9×109/L，hemoglobin of 3.3 g/dL，a platelet count of 147×109/L，absolute neutrophil count of 1.42×109/L，absolute lymphocyte count of 0.14×109/L，lactate dehydrogenase of 843 U/L，alanine aminotransferase of 283 U/L，and aspartate aminotransferase of 238 U/L.The patient was found to have acute renal failure on admission with serum creatinine of 13.9 mg/dL.Calculated creatinine clearance on admission was 7 mL/min.Chest X-ray revealed diffuse bilateral infiltrates.His anti-rejection regimen consisted of cyclosporine，azathioprine 50 mg once daily and prednisone 5 mg once daily.Continuous venovenous hemodialysis and hemofiltration were promptly started.His low hemoglobin level was attributed to upper gastrointestinal bleeding evidenced by a positive stool for occult blood test and an upper gastrointestinal scope that revealed gastric wall inflammation.The patient required a total of 12 units of packed red blood cells transfusion throughout the admission.
Two days after admission，the white blood count dropped to 0.98×109/L.Granulocyte colony-stimulating factor（300 mg subcutaneously once daily for 3 days）was then initiated and trimethoprim/sulfamethoxazole was discontinued.Viral pneumonia due to MERS CoV was suspected 6 days after admission.A nasopharyngeal swab as well as blood qualitative reverse transcription polymerase chain reaction assay（RTPCR）for MERS CoV were both positive.The patient’s clinical condition deteriorated，necessitating endotracheal intubation.
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Task 8 Translate the following sentences into Chinese.
1.A 44-year-old male presented to the emergency department on March 30，2014，complaining of generalized fatigue of a 3-day duration.
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2.On admission，he required 5-10 L/min of oxygen through facemask to maintain an oxygen saturation of 90%.Moreover，he had oliguria.
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3.His low hemoglobin level was attributed to upper gastrointestinal bleeding evidenced by a positive stool for occult blood test and an upper gastrointestinal scope that revealed gastric wall inflammation.
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4.Granulocyte colony-stimulating factor（300 mg subcutaneously once daily for 3 days）was then initiated and trimethoprim/sulfamethoxazole was discontinued.
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5.A nasopharyngeal swab as well as blood qualitative reverse transcription polymerase chain reaction assay（RT-PCR）for MERSCoV were both positive.
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