参考文献
[1]SIEGEL R L, et al.Cancer statistics[J]. CA Cancer J Clin, 2015.
[2]POSADAS E M, et al. Systemic therapy in renal cell carcinoma: advancing paradigms [J]. Oncology (Williston Park), 2012.
[3]MERCER T R, et al.Long noncoding RNAs: insights into functions[J]. Nat Rev Genet, 2009.
[4]ISIN M, et al. Long noncoding RNAs and neoplasia[J]. Clin Chim Acta, 2015.
[5]CONSORTIUM E P. An integrated encyclopedia of DNA elements in the human genome[J]. Nature, 2012.
[6]PONTING C P, et al.Evolution and functions of long noncoding RNAs[J]. Cell, 2009.
[7]PANDEY R R, et al. transcriptional and posttranscriptional programming by long noncoding RNAs[J]. Prog Mol Subcell Biol, 2011.
[8]MALOUF G G, et al. Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing[J]. Mol Oncol, 2015.
[9]CHIYOMARU T, et al. Long noncoding RNA HOTAIR is targeted and regulated by miR-141in human cancer cells[J]. J Biol Chem, 2014.
[10]CAI B, et al. Long noncoding RNA HOTAIR can serve as a common molecular marker for lymph node metastasis: a meta-analysis[J]. Tumour Biol, 2014.
[11]WU Y, et al. Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells[J]. Tumour Biol, 2014.
[12]SHI X, et al. Long non-coding RNAs: a new frontier in the study of human diseases[J]. Cancer Lett, 2013.
[13]ZHU L, et al. Long noncoding RNA MALAT-1 can predict metastasis and a poor prognosis: a meta-analysis[J]. Pathol Oncol Res, 2015.
[14]ZHANG H M, et al. Upregulation of long non-coding RNA MALAT1 correlates with tumor progression and poor prognosis in clear cell renal cell carcinoma[J].Tumour Biol, 2015.
[15]HIRATA H, et al. Long noncoding RNA MALAT1 promotes aggressive renal cell carcinoma through Ezh2 and interacts with miR-205[J]. Cancer Res, 2015.
[16]WAGENER N, et al.The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinomacells[J]. Int J Cancer, 2008.
[17]LIU L, et al. Enhancer of zeste homolog 2 (EZH2) promotes tumour cell migration and invasion via epigenetic repression of E-cadherin in renal cell carcinoma[J]. BJU Int, 2014.
[18]TSAI M C, et al. Long noncoding RNA as modular scaffold of histone modification complexes[J]. Science, 2010.
[19]HE H, et al. Epithelial-to-mesenchymal transition in renal neoplasms[J]. Adv Anat Pathol, 2014.
[20]MAJID S, et al. MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer[J]. Cancer Res, 2011.
[21]YOSHINO H, et al. Epithelialmesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma[J]. J Hum Genet, 2013.
[22]FANG Y, et al. Protein expression of ZEB2 in renal cell carcinoma and its prognostic significance in patient survival[J]. PLoS One, 2013.
[23]CHEN Z, et al. miRNA-205 is a candidate tumor suppressor that targets ZEB2 in renal cell carcinoma[J]. Oncol Res Treat, 2014.
[24]XIAO H, et al. lncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma[J]. Oncotarget, 2015.
[25]DAVIS I J, et al. Cloning of an alpha-TFEB fusion in renal tumors harboring the (6; 11) (p21; q13) chromosome translocation[J]. Proc Natl Acad Sci USA, 2003.
[26]QIAO H P, et al. Long non-coding RNA GAS5 functions as a tumor suppressor in renal cell carcinoma[J]. Asian Pac J Cancer Prev, 2013.
[27]MOURTADA M M, et al.GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer[J]. Oncogene, 2009.
[28]MURAKAMI Y. Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis[J]. Cancer Sci, 2005.
[29]YAO J, et al. Decreased expression of a novel lnc RNA CADM1-AS1 is associated with poor prognosis in patients with clear cell renal cell carcinomas[J]. Int J Clin Exp Pathol, 2014.
[30]KAFFER C R, et al. A transcriptional insulator at the imprinted H19/Igf2 locus[J]. Genes Dev, 2000.
[31]YANG F, et al. Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells[J]. FEBS J, 2012.
[32]MONNIER P, et al. H19 gene controls placental development through a miRNA[J]. Med Sci (Paris), 2013, 29.
[33]PIDSLEY R, et al. Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight[J]. Epigenetics, 2012.
[34]WANG L, et al. Down-regulated long non-coding RNA H19 inhibits carcinogenesis of renal cell carcinoma[J]. Neoplasma, 2015.
[35]SONG S, et al. RCCRT1 is correlated with prognosis and promotes cell migration and invasion in renal cell carcinoma[J]. Urology, 2014.
[36]KAYOH Y, et al.FGF signaling inhibitor, SPRY4, is evolutionarily conserved target of WNT signaling pathway in progenitor cells[J]. Int J Mol Med, 2006.
[37]KHAITAN D, et al. The melanomaupregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion[J]. Cancer Res, 2011.
[38]ZHANG H M, et al. High expression of long non-coding RNA SPRY4-IT1 predicts poor prognosis of clear cell renal cell carcinoma[J]. Int J Clin Exp Pathol, 2014.
[39]PANDEY G K, et al. The risk associated long noncoding RNA NABAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation[J]. Cancer Cell, 2014.
[40]XUE S, et al. Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma[J]. Int J Clin Exp Pathol, 2015.
[41]ZHONGH, et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases[J]. Cancer Res, 1999.
[42]IOANNOU M, et al. HIF-1alpha in colorectal carcinoma: review of the literature[J]. J BUON, 2015.
[43]BERTOZZID, et al. Characterization of novel antisense HIF-1alpha transcripts in human cancers[J]. Cell Cycle, 2011.
[44]THRASH-BINGHAM C A, et al.aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia[J]. J Natl Cancer Inst, 1999.
[45]ZHOU Y, et al.MEG3 noncoding RNA: a tumor suppressor[J]. J Mol Endocrinol, 2012.
[46]WANG M, HUANG T, LUO G, et al. Long non-coding RNA MEG3 induces renal cell carcinoma cells apoptosis by activating the mitochondrial pathway[J]. J Huazhong Univ Sci Technolog Med Sci, 2015.