参考文献
[1]LI H,ZHANG H,XU Y,et al.Versatile digital polymerase chain reaction chip design,fabrication,and image processing[J].Sensors and Actuators B:Chemical,2019,283:677-684.
[2]YIN J X,MOU L,YANG M Z,et al.Highly efficient capture of circulating tumor cells with low background signals by using pyramidal microcavity array[J].Analytica Chim ica Acta,2019,1060:133-141.
[3]OZKUMUR A Y,KANIK F E,TRUEB J T,et al.Interferometric detection and enumeration of viral particles using Si-based microfluidics[J].IEEE Journal of Selected Topics in Quantum Electronics,2019,25(1):1-7.
[4]BERENGUEL-ALONSO M,ORTIZ-GOMEZ I,FERNANDEZ B,et al.An LTCC monolithic m icroreactor for the synthesis of carbon dots with photoluminescence imaging of the reaction progress[J].Sensors and Actuators B:Chemical,2019,296:126613.1-126613.8.
[5]D I'AZ LANTADA A,DE BLAS ROMERO A,SCHWENTENWEIN M,et al.Monolithic 3D labs and organs-on-chips obtained by lithography-based ceramic manufacture[J].The International Journal of Advanced Manufacturing Technology,2017,93:3371-3381.
[6]HUANG B,WU H,BHAYA D,et al.Counting low-copy number proteins in a single cell[J].Science,2007,315(5808):81-84.
[7]REN K,ZARE R N.Chemical recognition in cell-imprinted polymers[J].ACS Nano,2012,6(5):4314-4318.
[8]BECKER H,GÄRTNER C.Polymer microfabrication technologies for microfluidic systems[J].Analytical & Bioanalytical Chemistry,2008,390(1):89-111.
[9]GRIFFITH L G,SWARTZ M A.Capturing comp lex 3D tissue physiology in vitro[J].Nature Reviews Molecular Cell Biology,2006,7(3):211-224.
[10]CHOI N W,CABODI M,HELD B,et al.Microfluidic scaffolds for tissue engineering[J].Nature Materials,2007,6(11):908-915.
[11]BEEBE D J,MOORE J S,BAUER J M,et al.Functional hydrogel structures for autonomous flow control inside m icrofluidic channels[J].Nature,2015,404(6778):588.
[12]SIEGEL A C,TANG S K Y T,NIJHUIS C A,et al.Cofabrication:a strategy for building multicomponent microsystems[J].Accounts of Chemical Research,2010,43(4):518-528.
[13]郑小林,鄢佳文,胡宁,等.微流控芯片的材料与加工方法研究进展[J].传感器与微系统,2011,30(06):1-4,7.
[14]林炳承,秦建华.图解微流控芯片实验室[M].北京:科学出版社,2008.
[15]SHAN C,CHEN F,YANG Q,et al.3D multi-microchannel helical m ixer fabricated by fem tosecond laser inside fused silica[J].Micromachines,2018,9(1):29.
[16]CALMO R,LOVERA A,STASSI S,et al.Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids[J].Sensors and Actuators,2019,B283(MAR.):298-303.
[17]REN K,ZHOU J,WU H.Materials for microfluidic chip fabrication[J].Accounts of Chemical Research,2013,46(11):2396-2406.
[18]TRAN V T,WEI Y F,LIAU W J,et al.Preparing of interdigitated microelectrode arrays for AC electrokinetic devices using inkjet printing of silver nanoparticles ink[J].Micromachines,2017,8(4):106.
[19]HE Y,WU W B,FU J Z.Rapid fabrication of paper-based microfluidic analytical devices with desktop stereolithography 3D printer[J].RSC Advances,2014,5(4):2694-2701.
[20]GAAL G,MENDES M,DE ALMEIDA T P,et al.Simplified fabrication of integrated m icrofluidic devices using fused deposition modeling 3D printing[J].Sensors and Actuators B:Chemical,2017,242:35-40.
[21]杨海峰.飞秒激光微纳加工技术与应用研究[D].镇江:江苏大学,2007.
[22]王树立.基于图案化微结构及表面的微纳流体控制[D].长春:吉林大学,2018.
[23]易宁波.基于微纳加工技术改性半导体材料及其光电器件制备研究[D].哈尔滨:哈尔滨工业大学,2018.
[24]范一强,王洪亮,张亚军.低成本聚合物微流控芯片加工技术综述[J].传感器与微系统,2019,38(5):7-11.
[25]李和太,李晔辰.硅片键合技术的研究进展[J].传感器世界,2002,9:6-10.
[26]罗怡,王晓东,王立鼎.聚合物微流控芯片的键合技术与方法[J].中国机械工程,2008,19(24):3012-3018.
[27]OH K W,AHN C H.A review of microvalves[J].Journal of Micromech Microeng,2006,16(5):13-39.
[28]YANG B,LIN Q.Planar micro-check valves exploiting large polymer compliance[J].Sensors and Actuators A:Physical,2007,134(1):186-193.
[29]THORSEN T,MAERKL S J,QUAKE S R.Microfluidic large-scale integration[J].Science,2002,298(5593):580-584.
[30]OH K W,PARK C,NAMKOONG K,et al.World-to-chip microfluidic interface with built-in valves for multichamber chip-based PCR assays[J].Lab on a Chip,2005,5(8):845-850.
[31]YANG Z,MAEDA R.A world-to-chip socket for microfluidic prototype development[J].Electrophoresis,2002,23(20):3474-3478.
[32]ZHANG J,SU X,XU J,et al.A point of care platform based on m icrofluidic chip for nucleic acid extraction in less than 1 minute[J].Biomicrofluidics,2019,13(3):034102.
[33]高兵兵.基于毛细力自驱动的微流控芯片及在POCT中的应用[D].南京:东南大学,2017.
[34]朱凯.阵列梯度表面液滴定向润湿机理及其在微流控器件中的应用[D].杭州:浙江工业大学,2018.
[35]LI Y,REN Y,LIU W,et al.On controlling the flow behavior driven by induction electrohydrodynamics in microfluidic channels[J].Electrophoresis,2017,38(7):983.
[36]WANG T,CHEN H,LIU K,et al.Janus Si micropillar arrays with thermal-responsive anisotropic wettability for manipulation of microfluid motions[J].ACS Applied Materials & Interfaces,2015,7(1):376.
[37]刘本东,张震,李德胜.微泵的分类及其研究的最新进展[J].北京工业大学学报,2018,44(6):17-29.
[38]陈昱.微流控技术中的微流体控制与应用[J].海峡科技与产业,2018(6):21-28.
[39]郑振,陈阳,李武宏,等.液滴微流控芯片技术及其在药物筛选中的应用[J].药学服务与研究,2016,16(3):163-169.
[40]OU X,CHEN P,HUANG X,et al.Microfluidic chip electrophoresis for biochemical analysis[J].Journal of Separation Science,2020,43:258-270.
[41]王新珏,祝莹,方群.基于微流控芯片的色谱技术的研究进展及其应用[J].色谱,2011,29(2):99-104.
[42]董娅妮,方群.微流控芯片毛细管电泳在蛋白质分离分析中的应用研究进展[J].色谱,2008,26(3):269-273.
[43]ZHOU J,XU J D,XIE Y,et al.Semi-crosslinked polyacrylamides as highresolution and dynamic self-coating sieving matrices for protein capillary electrophoresis[J].Chinese Science Bulletin,2008,53(19):2953-2957.
[44]徐溢,徐平洲,张剑,等.微流控芯片上电驱动在线富集技术的研究进展[J].化学通报,2007(9):655-661.
[45]高凡,王晓飞,张博.胶束电动色谱技术在蛋白质分离分析中的应用研究进展[J].分析化学,2019,47(6):805-813.
[46]吴春卉,姜有为,程鑫.微流控芯片在单细胞捕获中的应用[J].科技导报,2018,36(16):39-45.
[47]孙维维,罗爱芹,戴荣继,等.空间自由流Off-Gel等电聚焦耦合芯片[C]//中国化学会第十一届全国生物医药色谱及相关技术学术交流会,井冈山,F,2016.
[48]LIN F M,YU S Y,GU L,et al.In situ photo-immobilised pH gradient isoelectric focusing and zone electrophoresis integrated two-dimensional microfluidic chip electrophoresis for protein separation[J].Microchimica Acta,2015,182(13-14):2321-2328.
[49]YU S Y,XU J D,HUANG K J,et al.A novel method to predict protein aggregations using two-dimensional native protein microfluidic chip electrophoresis[J].Analytical Methods,2016,8:8306-8313.
[50]LIN F,ZHAO X,WANG J,et al.A novel microfluidic chip electrophoresis strategy for simultaneous,label-free,multi-protein detection based on a graphene energy transfer biosensor[J].Analyst,2014,139(11):2890-2895.
[51]LU Y,YU S Y,LIN F M,et al.Simultaneous label-free screening of G-quadruplex active ligands from natural medicine via a microfluidic chip electrophoresisbased energy transfer multi-biosensor strategy[J].Analyst,2017,142:4257-4264.
[52]耿利娜,邓玉林,陈辉,等.一种多维微流控电泳芯片及检测装置,检测方法:202010770908.6[P].2021-02-12.
[53]王新珏,祝莹,方群.基于微流控芯片的色谱技术的研究进展及其应用[J].色谱,2011,29(2):8-13.
[54]廖泽荣,李永瑞,古乐,等.基于微流控芯片的细胞外囊泡分离技术研究进展[J].色谱,2019,37(4):343-347.
[55]BURKLUND A,TADIMETY A,NIE Y,et al.Advances in diagnostic microfluidics[J].Advances in Clinical Chemistry,2020,95:71-72.
[56]ŠTĚPÁNOVÁS,KAŠI KA V.Analysis of proteins and peptides by electromigration methods in m icrochips[J].Journal of Separation Science,2017,40(1):228-250.
[57]SHI H,NIE K,DONG B,et al.Recent progress of m icrofluidic reactors for biomedical applications[J].Chemical Engineering Journal,2019,361:635-650.
[58]SURYAWANSHI P L,GUMFEKAR S P,BHANVASE B A,et al.A review on microreactors:Reactor fabrication,design,and cutting-edge applications[J].Chemical Engineering Science,2018,189:431-448.
[59]袁炜,刘卫卫,李倩,等.微反应器技术在聚合中的应用研究进展[J].高分子通报,2019(1):94-101.
[60]霍丹群,刘振,侯长军,等.微流控芯片光学检测技术在细胞研究中的应用与进展[J].分析化学,2010(9):136-144.
[61]MAO S F,LI W W,ZHANG Q,et al.Cell analysis on chip-mass spectrometry[J].TrAC Trends in Analytical Chemistry,2018,107:43-59.
[62]姬兰婷.基于表面等离子体效应的聚合物光波导器件研究[D].长春:吉林大学,2019.
[63]任益弘,朱君,李娜,等.纳米颗粒局域表面等离激元共振的光谱特性研究进展[J].激光杂志,2020,41(7):1-6.
[64]尹强.高通量生物传感器的光波导结构优化[D].重庆:重庆理工大学,2020.
[65]李春赫,马卓晨,胡昕宇,等.微流控拉曼检测芯片的制备与应用[J].中国激光,2021,48(2):0202010.
[66]徐亚萌,孔梅.基于硅基微环谐振器的折射率传感研究综述[J].半导体光电,2020,41(4):455-463.
[67]HEBERT P D N,CYW INSKA A,BALL S L,et al.Biological identifications through DNA barcodes[J].Proceedings of the Royal Society of London Series B:Biological Sciences,2003,270(1512):313-321.
[68]HUI W C,YOBAS L,SAMPER V D,et al.Microfluidic systems for extracting nucleic acids for DNA and RNA analysis[J].Sensors and Actuators A:Physical,2007,133(2):335-339.
[69]LIAO Z,WANG J F,ZHANG P J,et al.Recent advances in microfluidic chip integrated electronic biosensors for multip lexed detection[J].Biosensors and Bioelectronics,2018,12(121):272-280.
[70]LIAO Z,ZHANG Y,LI Y R,et al.Microfluidic chip coupled with optical biosensors for simultaneous detection of multiple analytes:A review[J].Biosensors and Bioelectronics,2019,2(126):697-706.
[71]UCHIYAMA K,HIBARA A,KIMURA H,et al.Thermallens microscope[J].Japanese Journal of Applied Physics,2000,39(Part 1,No.9A):5316-5322.