（三）实用指导
在本节中，程序步骤需要产生与报告的有效性结构域评估要素相对应的结果。
为了完成一个或多个有效性结构域系统评估，需要执行一个或多个系统评估，还要回答每个选定的问题。有预先确定的步骤用于编写系统评估（2009年CRD医疗卫生评估指导；Higgins等，2011；卫生技术评估核心模型手册，2012；2013年HTA快速药物模型；Moher等，2009），如表33至表42所示。
表33 从卫生技术评估核心模型评估要素中选择主题和问题
表34 研究问题的定义
表35 确定研究的纳入标准定义
（续表）
（续表）
表36 系统的证据搜寻
表37 选择研究
表38 数据提取
表39 方法学质量评估
表40 数据综合
表41 证据质量分级
表42 报告
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