抗生素
1.Do not prescribe grantcillin and dinnercillin.
—— Moshe Schein
【译文】别开抗生素给患者当补品或当饭吃。
2.Our arsenals for fighting off bacteria are so powerful … that we're in more danger from them than from the invaders.
—— Lewis Thomas.
【译文】我们用来击退细菌的军火库是如此强大……问题是它会比入侵的细菌带给我们更大的威胁。
3.Antibiotics for the fool is a tool which appears cool.But somebody pays the price as a rule.
—— Moshe Schein
【译文】对傻瓜来说抗生素是一种看起来很酷的工具,但最终将有人为此付出代价。
4.No amount of post-operative antibiotics can compensate for intra-operative mishaps and faulty technique, or can abort post-operative suppuration necessitating drainage.
—— Moshe Schein
【译文】术后再多的抗生素也不能弥补手术中的失误和技术缺陷,也不能避免必须通过引流来解决的术后化脓。
5.Prophylactic antibiotics will turn a third class surgeon into a second class but will never turn a second class surgeon into the first class one.
—— Owen H.Wangensteen, 1898——1981
【译文】预防性抗生素能把三等外科医生变成二等,但绝无可能把二等外科医生变成一等。
【点评】这个相互关系表述得准确又生动。
6.Historically, the most common errors in usage include the widespread use of antibiotic prophylaxis in clean surgery and the faulty timing of administration.The most common error today(in the use of prophylactic antibiotics in surgical practice)is continuation of the agents beyond the time necessary for maximal benefit.(https://www.daowen.com)
—— Ronald L.Nichols
【译文】历史上,最常见的抗生素应用错误是清洁手术中预防性抗生素的滥用以及给药时间的错误,而今天外科实践中预防性抗生素应用的最常见错误是持续应用时间获得最大效益所必需的时间。
7.Nietzsche once stated,"That which does not kill you only makes you stronger." While he was not necessarily referring to bacteria and their relationship to antibiotics, the quotation nonetheless applies.
—— Mikaela Chilstrom
【译文】尼采曾经说过,“那些不会杀死你的东西只会使你更强壮。”虽然他不一定指细菌与抗生素的关系,但这句话用在这很适合。
【点评】细数当下肆虐于各大医院ICU病房的耐甲氧西林金黄色葡萄球菌(MRSA)、耐万古霉素肠球菌(VRE)、产超广谱β-内酰胺酶(ESBLs)的肠杆菌以及多重耐药菌(MDROS)无一不是劫后余生的新生代。
8.The headline reads, "Docs say patients make them prescribe useless antibiotics." This puts a physician in roughly the same predicament as a serial killer.The latter says, "stop me before I kill again", while the former says, "stop me before I prescribe again."
—— Nicolas Martin
【译文】大标题上写着“医生说患者让他们开无用的抗生素”,这如同让医生陷入一个和连环杀手差不多的困境,后者说,“在我再次杀人之前阻止我”,而前者说,“在我再次开处方之前阻止我”。
【点评】这多么像中国医院抗生素的管理现状!

9.Antibiotics in trauma: sooner and more is better than less and longer.
—— Moshe Schein
【译文】创伤中的抗生素:早用、大剂量好过小量而长时间的用。
10.Start antibiotics prior to any emergency laparotomy; whether to continue administration after the operation depends on your findings.Know the target flora and use the cheapest and simplest regimen.The bacteria cannot be confused, nor should you be.
【译文】任何紧急剖腹手术前应开始使用抗生素;手术后是否继续给药取决于你的术中所见。明确目标菌群,使用最便宜和最简单的方案。细菌不要搞混淆,你也不要犯糊涂。