参考文献

[1]Gladman DD, Ibanez D, Urowitz MB, et al.Systemic lupus erythematosus disease activity index 2000[J].The Journal of rheumatology, 2002,29(2): 288—291.

[2]Mummert E, Fritzler MJ, Sjöwall C, et al.The clinical utility of anti-double-stranded DNA antibody and the challenges of their determination[J].Journal of immunological methods, 2018, 459: 11—19.

[3]Biesen R, Dähnrich C, Rosemann A, et al.Anti-dsDNA-NcX ELISA: dsDNA-loaded nucleosomes improve diagnosis and monitoring of disease activity in systemic lupus erythematosus[J].Arthritis research & therapy, 2011, 13(1): R26.

[4]Kim J M, Ihm CH, Sin DH, et al.Detection of anti-ENA and anti-dsDNA antibody using line immunoassay in systemic autoimmune diseases[J].The Korean journal of laboratory medicine, 2008, 28(5): 353—361.

[5]Zhao J, Wang K, Wang X, et al.The performance of diあ erent anti-dsDNA autoantibodies assays in Chinese systemic lupus erythematosus patients[J].Clinical rheumatology, 2018, 37(1): 139—144.

[6]Bizzaro N, Villalta D, Giavarina D, et al.Are anti-nucleosome antibody a better diagnostic marker than anti-dsDNA antibody for systemic lupus erythematosus? A systematic review and a study of metanalysis[J].Autoimmunity reviews, 2012, 12(2): 97—106.

[7]Min DJ, Kim SJ, Park SH, et al.Anti-nucleosome antibody: signif icance in lupus patients lacking anti-double-stranded DNA antibody[J].Clinical and experimental rheumatology, 2002, 20(1): 13—18.

[8]Su Y, Jia RL, Han L, et al.Role of anti-nucleosome antibody in the diagnosis of systemic lupus erythematosus[J].Clinical Immunology, 2007,122(1): 115—120.

[9]Amoura Z, Koutouzov S, Chabre H, et al.Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases:antinucleosome antibody of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus[J].Arthritis & Rheumatism:Oき　cial Journal of the American College of Rheumatology, 2000, 43(1): 76—84.

[10]Shoenfeld, Y, Meroni, PL, Gershwin ME, et al.Autoantibodies[M].3rd ed.Amsterdam: Elsevier, 2014.

[11]Schett G, Smolen J, Zimmermann C, et al.The autoimmune response to chromatin antigens in systemic lupus erythematosus: autoantibodies against histone H1 are a highly specif ic marker for SLE associated with increased disease activity[J].Lupus, 2002, 11(11): 704—715.

[12]Sui M, Lin Q, Xu Z, et al.Simultaneous positivity for anti-DNA, anti-nucleosome and anti-histone antibody is a marker for more severe lupus nephritis[J].Journal of clinical immunology, 2013, 33(2): 378—387.

[13]Kubo M, Ihn H, Yazawa N, et al.Prevalence and antigen specif icity of anti-histone antibody in patients with polymyositis/dermatomyositis[J].Journal of investigative dermatology, 1999, 112(5): 711—715.