附录 常用术语缩写词英汉对照

附录 常用术语缩写词英汉对照

缩写 英文全称 中文全称

2—OADC  2—oxo-acid dehydrogenase complex  2—氧酸脱氢酶复合体

A

AA  amino acid  氨基酸

AARD  ANA—associated rheumatic diseases  抗核抗体相关自身免疫病

AC  anti-cell  抗细胞

ACA  anti-centromere antibody  抗着丝粒抗体

ACL  anticardiolipin antibody  抗心磷脂抗体

ACR  American College of Rheumatology  美国风湿病学会

ADP  adenosine diphosphate  二磷酸腺苷

AFP  α—fetoprotein  甲胎蛋白

AGAA  anti-golgi appratus antibody  抗高尔基体抗体

Ago2  argonaute protein 2  Ago2蛋白

AHA  antihistone antibody  抗组蛋白抗体

AID  autoimmune diseases  自身免疫病

AIH  autoimmune hepatitis  自身免疫性肝炎

AIM  autoimmune myopathy  自身免疫性肌病

ALA  antilamin antibody  抗核纤层蛋白抗体

ALBIA  addressable laser bead immunoassay  可寻址激光珠免疫分析法

ALD  autoimmune liver disease  自身免疫性肝病

ALP  alkaline phosphatase  碱性磷酸酶

AMA  anti-mitochondrial antibody  抗线粒体抗体

AMA—M2  anti-mitochondrial antibody—M2  抗线粒体抗体—M2型

ANA  antinuclear antibody  抗核抗体

ANuA  anti-nucleosome antibody  抗核小体抗体

APL  acute promyelocytic leukemia   急性早幼粒细胞白血病

APS  antiphospholipid syndrome  抗磷脂综合征

ARS  aminoacyl-transfer ribonucleic acid synthetases  氨基酰tRNA合成酶

ASS  anti-synthetase syndrome  抗合成酶综合征

ATP  adenosine triphosphate  三磷酸腺苷

B

β2—MU  β2 microglobulin  β2—微球蛋白

BCOADC—E2  the E2 subunits of branched chain 2—oxo-acid  支链2—氧酸脱氢酶复合体—E2亚基dehydrogenase complex

BNP  B-type natriuretic peptide  B型钠尿肽

C

C3  complement component 3  补体C3

CA19—9  carbohydrate antigen 19—9  糖类抗原19—9

CA74—2  carbohydrate antigen 74—2  糖类抗原CA72—4

C—ANCA  cytoplasmic antineutrophil cytoplasmic antibody  胞浆型抗中性粒细胞胞浆抗体

CBs  Cajal bodies  卡哈尔体

CCP  cyclic citrullinated peptide  环瓜氨酸肽

CEA  carcinoembryonic antigen  癌胚抗原

CENP  centromere proteins  着丝粒蛋白

Cep  centrosomal protein  中心体蛋白

CH50  50%complement hemolysis  总补体溶血活性

CHB  congenital complete heart Block  完全性心脏传导阻滞

CIDP  chronic inflammatory demyelinating polyneuropathy  慢性炎性脱髓鞘性多发性神经病

CK  creatine kinase  肌酸激酶

CK—MB  creatine kinase myocardial band  肌酸激酶同工酶

cLED  controlled light emitting diode  可控发光二极管

CLIA  chemiluminescence immunoassay  化学发光免疫分析法

CLIFT  Crithidia Luciliae immunofluorescence test  绿蝇短膜虫免疫荧光法

CLIP—170  cytoplasmic linker protein—170  细胞质连接蛋白170

CLL  chronic lymphocytic leukemia  慢性淋巴细胞性白血病

C—NAP1  centrosomal Nek2—associated protein 1  中心体Nek2—相关蛋白1

cN1A  cytosolic 5′—nucleotidase 1A  胞浆5′—核苷酸酶1A

Cr  creatinine  肌酐

CRP  C—reactive protein  C—反应蛋白

CSF  cerebrospinal fluid  脑脊液

CTD  connective tissue disease  结缔组织病

CYFRA 21—1  cyto-keratin19 fragment antigen 21—1  细胞角质蛋白19片段抗原21—1

D

DBIL  direct Bilirubin  直接胆红素

DCA  dividing cell antigen  分裂细胞抗原

dcSSc  diffuse cutaneous systemic sclerosis  弥漫性皮肤型系统性硬化症

DFS  dense fine speckles 70  致密细颗粒70

DIB  dot immunoblot  斑点免疫印迹法

DIL  drug-induced lupus  药物性狼疮

DLCM  digital liquid chip method  数码液相芯片技术

DLE  discoid lupus erythematosus  盘状红斑狼疮

DM  dermatomyositis  皮肌炎

DNA  deoxyribonucleic acid  脱氧核糖核酸

DNP  deoxyribonucleoprotein  脱氧核糖核蛋白

dsDNA  double stranded deoxyribonucleic acid  双链DNA

E

E3  dihydrolipoamide dehydrogenase  二氢硫辛酸脱氢酶

E3BP  E3—binding protein  二氢硫辛酸脱氢酶结合蛋白

EDC4  enhancer of mRNA decapping 4 mRNA  去帽增强子4

EEA1  early endosome antigen 1  早期内体抗原1

EJ  glycyl tRNA synthetase  甘氨酰tRNA合成酶

ELISA  enzyme linked immunosorbent assay  酶联免疫吸附试验

ELMP  EUROLineMaster Plus  欧蒙全自动免疫印迹仪

ENA  extractable nuclear antigen  可提取核抗原

ESR  erythrocyte sedimentation assay  红细胞沉降率

EULAR  European League Against Rheumatism  欧洲抗风湿病防治联盟

F

FEV1  forced expiratory volume in one second  一秒用力呼气容积

FIB  fibrinogen  纤维蛋白原

FITC  fluorescein isothiocyanate  异硫氰酸荧光素

FT3  free triiodo thyronine  游离三碘甲腺原氨酸

G

G  glycine  甘氨酸

GBM  glomerular basement membrane  肾小球基膜

Gems  Gemini of Cajal bodies  卡哈尔体的双子星

GGT  γ—glutamyltransferase  γ谷氨酰基转移酶

GLB  globulin  球蛋白

GLDH  glutamate dehydrogenase  谷氨酸脱氢酶

GOT  glutamic-oxaloacetic transaminase  谷草转氨酶

gp210  glycoprotein—210  糖蛋白210

GPT  glutamic-pyruvic transaminase  谷丙转氨酶

GRASP—1  glutamate receptor interacting protein-associated  谷氨酸受体相互作用蛋白相关蛋白1 protein 1

GTP  guanosine triphosphate 鸟苷三磷酸

H

H  histone  组蛋白

Ha  tyrosyl-tRNA synthetase  酪氨酰tRNA合成酶

HBV  hepatitis B virus  乙型肝炎病毒

HCV  hepatitis C virus  丙型肝炎病毒

HIV  human immunodeficiency virus  人类免疫缺陷病毒

HLA—B27  human leukocyte antigen B27  人白细胞抗原B27

HMG—1  high-mobility group 1 domain  高迁移率族蛋白—1结构域

hnRNP  heterogeneous nuclear ribonucleoprotein  异质性胞核核糖核蛋白

HP1α  heterochromatin protein 1α  异染色体蛋白1α

HsEg5  homo sapiens Eg5  纺锤体驱动蛋白Eg5

I

IBD  integrase binding domain  整合酶结合域

ICAP  international consensus on ANA patterns  国际抗核抗体荧光核型共识

IFA  indirect immunofluorescent assay  间接免疫荧光法

IIM  idiopathic inflammatory myopathies  特发性炎症性肌病

IL—10  interleukin 10  白介素10

IL—6  interleukin 6  白介素6

ILD  interstitial lung disease  间质性肺病

IMNM  immune-mediated necrotizing myopathy  免疫介导的坏死性肌病

IMPDH2  inosine monophosphate dehydrogenase 2  肌苷单磷酸脱氢酶2

INCENP  inner centromere protein  内着丝粒蛋白

IP  immunoprecipitation  免疫沉淀法

IP—MS  immunoprecipitation-mass spectrometry  免疫沉淀—质谱联用

J

JCA  juvenile chronic arthritis  幼年慢性关节炎

JDM  juvenile dermatomyositis  幼年型皮肌炎

JIA  juvenile idiopathic arthritis  幼年特发性关节炎

Jo—1  histidyl tRNA synthetase  组氨酰tRNA合成酶

K

K  Kalium  钾

KIF11  kinesin family member 11  驱动蛋白家族成员11

KIF20B  kinesin family member 20B  驱动蛋白家族成员20B

KS  asparaginyl-tRNA synthetase  天冬氨酰tRNA合成酶

L

LAC  lupus anticoagulants  狼疮抗凝物

LAM  La-type ribonucleic acid-binding motif  La型核糖核酸结合域

LAP  lamina-associated protein  核纤层相关蛋白

LBPA  lysobisphosphatidic acid  溶血磷脂酸

LBR  lamins B receptor  核纤层蛋白B受体

LC—1  Liver cytosol specific antibody type 1  肝溶质Ⅰ型抗原

lcSSc  limited cutaneous systemic sclerosis  局限性皮肤型系统性硬化症

LDH  lactate dehydrogenase  乳酸脱氢酶

LE  lupus erythematosus  红斑狼疮

LEDGFp75  lens epithelium-derived growth factor p75  晶状体上皮来源生长因子p75

LIA  line immunoassay  线性免疫印迹法

LKM—1  liver/kidney microsome type 1  肝肾微粒体Ⅰ型抗原

LN  lupus nephritis  狼疮性肾炎

M

MAA  myositis-associated autoantibody  肌炎相关抗体

Mb  myoglobin  肌红蛋白

MCA  mitotic chromosomal autoantigen  有丝分裂染色体自身抗原

MCTD  mixed connective tissue disease  混合性结缔组织病

MDA5  melanoma differentiation-associated protein 5  黑色素瘤分化相关蛋白5

MeCP2  methyl CpG binding protein 2  甲基CpG结合蛋白2

miRNA  microRNA  微RNA

MPO  myeloperoxidase  髓过氧化物酶

MPP1  M-phase phosphoprotein 1  M期磷酸蛋白1

mRNA  messenger RNA  信使RNA

MS  multiple sclerosis  多发性硬化症

MSA  myositis-specific antibody  肌炎特异性抗体

MTOC  microtubule organizing center  微管形成中心

N

NE  nuclear envelope  核膜

NM Ⅱ  non-muscle myosin Ⅱ  非肌肉肌球蛋白Ⅱ

NMP—22  nuclear matrix protein 22  核基质蛋白22

NOR  nucleolus organizer regions  核仁组织区

NOR—90  nucleolus-organizing regions—90kDa  核仁组织区蛋白90 kDa

NPC  nuclear pore complex  核孔复合体

NPSLE  neuropsychiatric symptoms associated with SLE  神经精神性狼疮

NuMA  nuclear mitotic apparatus protein  核有丝分裂器蛋白

nup62  nucleoporin p62  核孔蛋白p62

NXP—2  nuclear matrix protein 2  核基质蛋白2

O

OGDC—E2  the E2 subunits of the 2—oxo-glutarate  2—酮戊二酸脱氢酶复合体—E2亚基dehydrogenase complex

OJ  isoleucyl tRNA synthetase 异亮氨酰tRNA合成酶抗体

P

P—ANCA  perinuclear antineutrophil cytoplasmic antibody  核周型抗中性粒细胞胞浆抗体

PA  Prealbumin  前白蛋白

PAR(AA)platelet  aggregation rate (arachidonic acid induced)  血小板聚集率(花生四烯酸诱导)

PB  processing bodies  P—小体

PBC  primary biliary cholangitis  原发性胆汁性胆管炎

PBS  phosphate buffer saline  磷酸缓冲液

PCM  pericentriolar material  中心粒外周物质

PCNA  proliferating cell nuclear antigen  增殖细胞核抗原

PCNT  pericentrin  中心粒周蛋白

PDC—E1α  the E1α subunits of the pyruvate dehydrogenase  丙酮酸脱氢酶复合体— E1α亚基complex

PDC—E2  the E2 subunits of the pyruvate dehydrogenase  丙酮酸脱氢酶复合体—E2亚基complex

PDGFR  platelet derived growth factor receptor  血小板衍生生长因子受体

Peg—IFN—α/RBV  pegylated interferon—α/ ribavirin  乙二醇干扰素—α/利巴韦林

PL—12  alanyl tRNA synthetase  丙氨酰tRNA合成酶

PL—7  threonyl tRNA synthetase  苏氨酰tRNA合成酶

PM  polymyositis  多发性肌炎

PM—Scl  polymyositis-scleroderma  多发性肌炎/硬皮病

PMAT  particle-based multi-analyte technology  基于粒子的多分析物技术

PML  promyelocytic leukemia 早幼粒细胞白血病

POLR3A RNA  polymerase III subunit A  RNA聚合酶Ⅲ亚单位A

POLR3K RNA  polymerase III subunit K  RNA聚合酶Ⅲ亚单位K

PR3   proteinase 3  蛋白酶3

pre-mRNA  precursor mRNA  前信使RNA

PSC  primary sclerosing cholangitis  原发性硬化性胆管炎

PSIP1  PC4 and SFRS1 interacting protein 1  PC4和SFRS1相互作用蛋白1

PTMs  post-translational modifications  翻译后修饰

R

RA  rheumatoid arthritis  类风湿关节炎

RARα  retinoid acid receptor α  维甲酸受体α

RBCC/TRIM  N-terminal RING finger/B-box/coiled coil /tripartite motif  N端指环/B盒/卷曲螺旋/三重结构域

RBV  ribavirin  利巴韦林

RF  rheumatoid factor  类风湿因子

RIA  radioimmunoassay  放射免疫测定

Rib—P  ribosomal P  核糖体P蛋白

RLU  relative light units  相对发光强度

RNA  ribonucleic acid  核糖核酸

RNAi RNA  interference  RNA干扰

RNAPI RNA  polymerase I  RNA聚合酶I

RNAPII RNA  polymerase II  RNA聚合酶II

RNAPIII RNA  polymerase III  RNA聚合酶III

RNase MRP  human RNasemitochondrial RNA processing complex  人核糖核酸酶线粒体RNA加工复合体

RNP  ribonucleoprotein  核糖核蛋白

RNP—A  ribonucleoproteins—A  核糖核蛋白A

RNP—C  ribonucleoproteins—C  核糖核蛋白C

RR  rods and rings  棒环状

RRMRNA  recognition motif  RNA识别域

rRNA  ribosomal RNA  核糖体RNA

S

SAA  Serumamyloid A  血清淀粉样蛋白A

SAE  small ubiquitin-like modifier activating enzyme  小泛素样修饰激活酶

SARD  systemic autoimmune rheumatic disease  系统性自身免疫病

SBM  short basic motif  短基本结构域

Scl—70  Scleroderma 70 —

SDS—PAGE  sodium dodecylsulphate polyacrylamide gel electrophoresis  十二烷基硫酸钠聚丙烯酰胺凝胶电泳

SIM  SUMO—interacting motif SUMO 相互作用区域

SLA/LP  soluble liver antigen/liver-pancreas  可溶性肝抗原/肝胰腺

SLE  systemic lupus erythematosus  系统性红斑狼疮

SLEDAI—2K  SLE disease activity index 2000  系统性红斑狼疮疾病活动指数2000

Sm  Smith  史密斯蛋白

SMA  smooth muscle antibody  平滑肌抗体

SMN  survival of motor neuron proteins  运动神经元生存蛋白

snRNA  small nuclear RNA  核小RNA

snRNP  small nuclear ribonucleoprotein  核小核糖核蛋白

Sp100  speckled protein 100  斑点蛋白100

SPN  spindle pole-nucleus  纺锤体极核

SRP  signal-recognition particle  信号识别粒子

SS  Sjogren’s syndrome  干燥综合征

SSA  Sjögren’s-syndrome-related antigen A   干燥综合征相关抗原A

SSB  Sjögren’s-syndrome-related antigen B   干燥综合征相关抗原B

SSc  systemic sclerosis 系统性硬化症

ssDNA  single-stranded deoxyribonucleic acid  单链DNA

SUMO  small ubiquitin-related modifier protein  小分子泛素相关修饰物蛋白

T

TBIL  total bilirubin  总胆红素

TIBC  total Iron binding capacity  总铁结合力

TIF1γ  transcriptional intermediary factor 1 γ  转录中间因子1γ

topo I  topoisomerase I  拓扑异构酶I

Tpr  translocated promoter region  转录启动子区域

TRIM  tripartite motif  三结构域蛋白

tRNA  transfer RNA  转运RNA

TRNC6A  trinucleotide repeat containing adaptor 6A  三核苷酸重复的衔接蛋白6A

TSH  thyroid-stimulating hormone  促甲状腺激素

U

U1—snRNP  U1 small nuclear ribonucleoprotein  U1核小核糖核蛋白

U3—snoRNP  U3 small nucleolar ribonucleoprotein  U3核仁小核糖核蛋白

UCTD  undifferentiated connective tissue disease  未分化结缔组织病

UIBC  unsaturated iron binding capacity  不饱和铁结合力

URIC  uric acid  尿酸

W

W  tryptophan  色氨酸

WB  western-blot  蛋白质免疫印迹

Z

ZO phenylalanyl-tRNA synthetase 苯丙氨酰tRNA合成酶抗体