参考文献
邓小燕，王贵学. 动脉系统中致动脉粥样性脂质的浓度极化现象［J］. 中国科学（C辑）, 2002, 32（6）: 559-567.
邓小燕，王贵学，杨杨. 扰动流条件下模拟血小板在半透膜壁上的黏附实验［J］. 中国科学通报, 2003, 48（20）: 2137-2140.
危当恒，王贵学，唐朝君，等. 狭窄血管远心端低密度脂蛋白浓度极化促进动脉粥样硬化形成［J］. 生理学报, 2007, 59（6）: 831-839.
危当恒.低密度脂蛋白浓度极化对动脉粥样硬化形成的影响及其机制［D］. 重庆：重庆大学，2006.
王贵学, 罗诗遂, 邓小燕. 脂质浓度极化现象与动脉粥样硬化血流动力学成因探讨［J］. 中国动脉硬化杂志, 2002, 10（39）: 49-52.
Avgerinos N A, Neofytou P. Mathematical modelling and simulation of atherosclerosis formation and progress: a review［J］. Ann Biomed Eng, 2019, 47（8）: 1764-1785.
Baeyens N, Bandyopadhyay C, Coon B G, Yun S, Schwartz M A. Endothelial fluid shear stress sensing in vascular health and disease［J］. J Clin Invest, 2016, 126（3）: 821-828.
Catapano A L, Pirillo A, Norata G D. New pharmacological approaches to target PCSK9［J］. Curr Atheroscler Rep, 2020, 22（7）: 24.
Davies P F. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology［J］. Nat Clin Pract Cardiovasc Med, 2009, 6（1）: 16-26.
Deng X, Wang G. Concentration polarization of atherogenic lipids in the arterial system［J］. Sci China C Life Sci, 2003, 46（2）: 153-164.
Fang L, Liu C, Miller Y I. Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis［J］. Transl Res, 2014, 163（2）: 99-108.
Fan Z, Liu X, Zhang P, Gu J, et al. Transfer of low-density lipoproteins in coronary artery bifurcation lesions with stenosed side branch: numerical study［J］. Comput Math Methods Med, 2019, 2019: 5297284.
Fatouraee N, Deng X, Champlain A, et al. Concentration polarization of low density lipoproteins （LDL） in the arterial system［J］. Ann N Y Acad Sci, 1998, 858: 137-146.
Ference B A , Ginsberg H N, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel［J］. Eur Heart J, 2017, 38（32）: 2459-2472.
Fernández-Friera L, Fuster V, López-Melgar B, et al. Normal LDL-cholesterol levels are associated with subclinical atherosclerosis in the absence of risk factors［J］. J Am Coll Cardiol, 2017, 70（24）: 2979-2991.
Getz G S, Reardon C A. Animal models of atherosclerosis［J］. Arterioscler Thromb Vasc Biol, 2012, 32（5）: 1104.(https://www.daowen.com)
Libby P, Ridker P M, Hansson G K. Progress and challenges in translating the biology of atherosclerosis［J］. Nature, 2011, 473（7347）: 317-325.
Mahmoudi M, Farghadan A, McConnell D R, et al. The story of wall shear stress in coronary artery atherosclerosis: biochemical transport and mechanotransduction［J］. J Biomech Eng, 2021, 143（4）: 041002.
Naiki T, Karino T. Visualization of flow-dependent concentration polarization of macromolecules at the surface of a cultured endothelial cell monolayer by means of fluorescence microscopy［J］. Biorheology, 2000, 37（5-6）: 371-384.
Naiki T, Sugiyama H, Tashiro R, et al. Flow-dependent concentration polarization of plasma proteins at the luminal surface of a cultured endothelial cell monolayer［J］. Biorheology, 1999, 36（3）: 225-241.
Roustaei M, Nikmaneshi M R, Firoozabadi B. Simulation of Low Density Lipoprotein （LDL） permeation into multilayer coronary arterial wall: interactive effects of wall shear stress and fluid-structure interaction in hypertension［J］. J Biomech, 2018, 67: 114-122.
Sabatine M S. PCSK9 inhibitors: clinical evidence and implementation［J］. Nat Rev Cardiol, 2019, 16（3）: 155-165.
Schlegel A. Zebrafish models for dyslipidemia and atherosclerosis research［J］. Front Endocrinol （Lausanne）, 2016（7）: 159.
Souilhol C, Serbanovic-Canic J, Fragiadaki M, et al. Endothelial responses to shear stress in atherosclerosis: a novel role for developmental genes［J］. Nat Rev Cardiol, 2020, 17（1）: 52-63.
Stoletov K, Fang L, Choi S H, et al. Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish［J］. Circ Res, 2009, 104（8）: 952-960.
Vedder V L, Aherrahrou Z, Erdmann J. Dare to compare. Development of atherosclerotic lesions in human, mouse, and zebrafish［J］. Front Cardiovasc Med, 2020, 7: 109.
Vincent P E, Weinberg P D. Flow-dependent concentration polarization and the endothelial glycocalyx layer: multiscale aspects of arterial mass transport and their implications for atherosclerosis［J］. Biomech Model Mechan, 2014, 13（2）: 313-326.
Wang G X, Deng X Y, Guidoin R. Concentration polarization of macromolecules in canine carotid arteries and its implication for the localization of atherogenesis［J］. J Biomech, 2003, 36（1）: 45-51.
Winkel L C, Hoogendoorn A, Xing R, et al. Animal models of surgically manipulated flow velocities to study shear stress-induced atherosclerosis［J］. Atherosclerosis, 2015, 241（1）: 100-110.
Wolf D, Ley K. Immunity and inflammation in atherosclerosis［J］. Circ Res, 2019, 124（2）: 315-327.
Xie X, Tan j, Wei D H, et al. In vitro and in vivo investigations on the effects of low-density lipoprotein concentration polarization and haemodynamics on atherosclerotic localization in rabbit and zebrafish［J］. J R Soc Interface, 2013, 10（82）: 20121053.