参考文献
刘华,王贵学,叶林奇,等. 一种可控的切应力及LDL浓度极化动物模型的建立及对动脉粥样硬化的影响[J]. 第三军医大学学报,2009, 31(12): 1981-1985.
危当恒,王贵学,唐朝君,等. 局部狭窄血管远心端流场数值模拟和PIV测定[J]. 南华大学学报:医学版, 2010, 38(1): 24-26.
王贵学,罗向东,欧阳克清,等. 剪切应力对毛细血管内皮细胞代谢的影响[J]. 生物物理学报, 1993, 3(1): 178-185.
吴孟津,危当恒,王贵学,等. 低剪切应力促进基质细胞衍生因子1在动脉粥样硬化斑块中表达[J]. 中国动脉硬化杂志, 2006, 12(14): 1028-1030.
Ajami N E, Gupta S, Maurya M R, et al. Systems biology analysis of longitudinal functional response of endothelial cells to shear stress[J]. Proc Natl Acad Sci USA, 2017, 114(41): 10990-10995.
Aulak K S, Barnes J W, Tian L, et al. Specific O-GlcNAc modification at ser-615 modulates eNOS function[J]. Redox Biol, 2020, 36: 101625.
Back M, Yurdagul A Jr, Tabas I, et al. Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities[J]. Nat Rev Cardiol, 2019, 16(7): 389-406.
Baeyens N, Bandyopadhyay C, Coon B G, et al. Endothelial fluid shear stress sensing in vascular health and disease[J]. J Clin Invest, 2016, 126(3): 821-828.
Bondareva O, Tsaryk R, Bojovic V, et al. Identification of atheroprone shear stress responsive regulatory elements in endothelial cells[J]. Cardiovasc Res, 2019, 115(10): 1487-1499.
Brown A J, Teng Z, Evans P C, et al. Role of biomechanical forces in the natural history of coronary atherosclerosis[J]. Nat Rev Cardiol, 2016, 13(4): 210-220.
Budatha M, Zhang J, Zhuang Z W, et al. Inhibiting integrin α5 cytoplasmic domain signaling reduces atherosclerosis and promotes arteriogenesis[J]. J Am Heart Assoc, 2018, 7(3): e007501.
Chen B P, Li Y S, Zhao Y, et al. DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress[J]. Physiol Genomics, 2001, 7(1): 55-63.
Chen J, Green J, Yurdagul A J, et al. αvβ3 integrins mediate flow-induced NF-KB activation, proinflammatory gene expression, and early atherogenic inflammation[J]. Am J Pathol, 2015, 185(9): 2575-2589.
Chen X, Qian S, Hoggatt A, et al. Endothelial cell-specific deletion of P2Y2 receptor promotes plaque stability in atherosclerosis-susceptible apoe-null mice[J]. Arterioscler Thromb Vasc Biol. 2017, 37(1): 75-83.
Chen Z, Oliveira S, Zimnicka A M, et al. Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells[J]. Mol Biol Cell, 2018, 29(10): 1190-1202.
Chistiakov D A, Orekhov A N, Bobryshev Y V. Contribution of neovascularization and intraplaque haemorrhage to atherosclerotic plaque progression and instability[J]. Acta Physiol (Oxf), 2015, 213(3): 539-553.
Chiu J J, Chien S. Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives[J]. Physiol Rev, 2011, 91(1): 327-387.
Chiu J J, Usami S, Chien S. Vascular endothelial responses to altered shear stress: pathologic implications for atherosclerosis[J]. Ann Med, 2009, 41(1): 19-28.
Civelek M, Manduchi E, Riley R J, et al. Coronary artery endothelial transcriptome in vivo: identification of endoplasmic reticulum stress and enhanced reactive oxygen species by gene connectivity network analysis[J]. Circ Cardiovasc Genet, 2011, 4(3): 243-252.
Cox C D, Bae C, Ziegler L, et al. Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension[J]. Nat Commun, 2016, 7: 10366.
Dunn J, Qiu H, Kim S, et al. Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis[J]. J Clin Invest, 2014, 124(7): 3187-3199.
Fang Y, Wu D, Birukov K G. Mechanosensing and mechanoregulation of endothelial cell functions[J]. Compr Physiol, 2019, 15, 9(2): 873-904.
Fan R, Tang D, Yang C, et al. Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: an IVUS-based fluid-structure interaction multi-patient study[J]. Biomed Eng Online, 2014, 13(1): 32.
Feaver R E, Gelfand B D, Wang C, et al. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation[J]. Circ Res, 2010, 106(11): 1703-1811.
Finney A C, Stokes K Y, Pattillo C B, et al. Integrin signaling in atherosclerosis[J]. Cell Mol Life Sci, 2017, 74(12): 2263-2282.
Gimbrone M A, Garcia-Cardena G. Endothelial cell dysfunction and the pathobiology of atherosclerosis[J]. Circ Res, 2016, 118 (4): 620-636.
Gomez D, Owens G K. Smooth muscle cell phenotypic switching in atherosclerosis[J]. Cardiovasc Res, 2012, 95(2): 156-164.
Hong F F, Liang X Y, Liu W, et al. Roles of eNOS in atherosclerosis treatment[J]. Inflamm Res, 2019, 68(6): 429-441.
Iring A, Jin Y J, Albarrán-Juárez J, et al. Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure[J]. J Clin Invest, 2019, 129(7): 2775-2791.
Jiang Y Z, Manduchi E, Stoeckert C J, et al. Arterial endothelial methylome: differential DNA methylation in atherosusceptible disturbed flow regions in vivo[J]. BMC Genomics, 2015, 16: 506.(https://www.daowen.com)
Koskinas K C, Sukhova G K, et al. Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress[J]. Arterioscler Thromb Vasc Biol, 2013, 33(7): 1494-1504.
Kumar S, Williams D, Sur S, et al. Role of flow-sensitive microRNAs and long noncoding RNAs in vascular dysfunction and atherosclerosis[J]. Vascul Pharmacol, 2019, 114: 76-92.
Li X, Yang Q, Wang Z, et al. Shear stress in atherosclerotic plaque determination[J]. DNA Cell Biol, 2014, 33(12): 830-838.
Liu J, Wang Y, Goh W I, et al. Talin determines the nanoscale architecture of focal adhesions[J]. Proc Natl Acad Sci USA, 2015, 112(35): e4864-4873.
Ni C W, Qiu H, Rezvan A, et al. Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow[J]. Blood, 2010, 116(15): e66-73.
Pedrigi R M, Poulsen C B, Mehta V V, et al. Inducing persistent flow disturbances accelerates atherogenesis and promotes thin cap fibroatheroma development in D374Y-PCSK9 hypercholesterolemic minipigs[J]. Circulation, 2015, 132(11): 1003-1012.
Petsophonsakul P, Furmanik M, Forsythe R, et al. Role of vascular smooth muscle cell phenotypic switching and calcification in aortic aneurysm formation[J]. Arterioscler Thromb Vasc Biol, 2019, 39(7): 1351-1368.
Qiu J, Lei D, Hu J, et al. Effect of intraplaque angiogenesis to atherosclerotic rupture-prone plaque induced by high shear stress in rabbit model[J]. Regen Biomater, 2017, 4(4): 215-222.
Qiu J, Wang G, Hu J, et al. Id1-induced inhibition of p53 facilitates endothelial cell migration and tube formation by regulating the expression of beta1-integrin[J]. Mol Cell Biochem, 2011, 357(1-2): 125-133.
Reneman R S, Arts T, Hoeks A P. Wall shear stress-an important determinant of endothelial cell function and structure-in the arterial system in vivo. Discrepancies with theory[J]. J Vasc Res, 2006, 43(3): 251-269.
Rosenson R S, Brewer H B, Ansell B J, et al. Dysfunctional HDL and atherosclerotic cardiovascular disease[J]. Nat Rev Cardiol, 2016, 13(1): 48-60.
Samady H, Eshtehardi P, McDaniel M C, et al. Coronary artery wall shear stress is associated with progression and transformation of atherosclerotic plaque and arterial remodeling in patients with coronary artery disease[J]. Circulation, 2011, 124(7): 779-788.
Souilhol C, Serbanovic-Canic J, Fragiadaki M, et al. Endothelial responses to shear stress in atherosclerosis: a novel role for developmental genes[J]. Nat Rev Cardiol, 2020, 17(1): 52-63.
Steward R Jr, Tambe D, Hardin C C, et al. Fluid shear, intercellular stress, and endothelial cell alignment[J]. Am J Physiol Cell Physiol, 2015, 308(8): C657-664.
Stone G, Maehara A, Lansky A, et al. Prospective natural-history study of coronary atherosclerosis[J]. New Engl J Med, 2011, 364 (3): 226-235.
Stone P H, Saito S, Takahashi S, et al. Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study[J]. Circulation, 2012, 126(2): 172-181.
Suvorava T, Cortese-Krott M M. Exercise-induced cardioprotection via eNOS: a putative role of red blood cell signaling[J]. Curr Med Chem, 2018, 25(34): 4457-4474.
Timmins L H, Molony D S, Eshtehardi P, et al. Oscillatory wall shear stress is a dominant flow characteristic affecting lesion progression patterns and plaque vulnerability in patients with coronary artery disease[J]. J R Soc Interface, 2017, 14(127): 20160972.
Wang G X, Cai S X, Rao X C, et al. The phenomenon of cell membrane tensile stress accumulation and its effect on endothelin-1 secretion by vascular endothelial cells[J]. Colloid Surface B, 2003(28): 273-278.
Wang G, Cai S, Deng X, et al. Secretory response of endothelin-1 in cultured human glomerular microvascular endothelial cells to shear stress[J]. Biorheology, 2000, 37(4): 291-299.
Wang G X, Cai S X, Wang P Q, et al. Shear-induced changes in endothelin-1 secretion of microvascular endothelial cells[J]. Microvasc Res, 2002, 63(2): 209-217.
Wang Y, Qiu J, Luo S, et al. High shear stress induces atherosclerotic vulnerable plaque formation through angiogenesis[J]. Regen Biomater, 2016, 3(4): 257-267.
Wentzel J J, Chatzizisis Y S, Gijsen F J, et al. Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions[J]. Cardiovasc Res, 2012, 96(2): 234-243.
White S J, Hayes E M, Lehoux S, et al. Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress[J]. J Cell Physiol, 2011, 226(11): 2841-2848.
Yahagi K, Kolodgie F D, Otsuka F, et al. Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis[J]. Nat Rev Cardiol, 2016, 13(2): 79-98.
Yang Q, Xu J, Ma Q, et al. PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis[J]. Nat Commun, 2018, 9(1): 4667.
Yun S, Budatha M, Dahlman J E, et al. Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling[J]. Nat Cell Biol, 2016, 18(10): 1043-1053.
Zeng Y, Zhang X F, et al. The role of endothelial surface glycocalyx in mechanosensing and transduction[J]. Adv Exp Med Biol, 2018, 1097: 1-27.
Zhang K, Chen Y, Zhang T, et al. A novel role of Id1 in regulating oscillatory shear stress-mediated lipid uptake in endothelial cells[J]. Ann Biomed Eng, 2018, 46(6): 849-863.
Zhou J, Li Y S, Chien S. Shear stress-initiated signaling and its regulation of endothelial function[J]. Arterioscler Thromb Vasc Biol, 2014, 34(10): 2191-2198.