5.1.1 Melanoma-specific criteria
Atypical pigment network:Brown-black network with irregular meshes and irregularly distributed lines of different thickness(high specificity for the diagnosis of melanoma).
Irregular dots and/or globules:Brown-black or gray,dots and globules of different size,irregularly distributed within the lesion.
Irregular blotches:Black,brown,or gray areas with irregular shape and/or distribution.
Irregular streaks and/or pseudopods:Radial lines irregularly distributed at the periphery of the lesion(streaks),sometimes with a bulbous projection at their peripheral ending(pseudopods).
Regression structures:Melanoma with regression structures appears in the flat area of the lesion and may exhibit as either white scarlike areas corresponding to fibrosis or bluegray areas(peppering)corresponding to melanophages.(https://www.daowen.com)
Blue-white veil:Melanoma with blue-white veil appears in the elevated part of the lesion,which is blue-gray or blue-white,diffuse and irregular pigmentation.
Irregular vascular structures:Polymorphous vessels,coexistence of dotted,linear,or hairpin vessels in the same lesion.
Due to the specific skin anatomy,pigmented melanocytic lesions on the certain locations(face,palms,soles,and nails)show unique dermoscopic features.