Questions

1.Can transdermal drug delivery technologies be used for the extraction of tissue fluid and liquid biopsy？What might be the advantages and limitations of each technology？（see extended reading 5）

2.What should be taken into particular consideration for the transdermal delivery of biomacromolecules compared to small molecule drugs？

3.Can transdermal drug delivery technologies be used for the delivery of cells or even tissues？What are the application prospects？(https://www.daowen.com)

4.Taking the application of microneedles in tumor therapy as an example，what are the ideal release modes of chemotherapeutic drugs and immune checkpoint inhibitors respectively？How can we design polymer microneedles to meet these modes？

5.What are the prospects of 3D printing technology in transdermal drug delivery？