参考文献
［1］Leon MB，Smith CR，Mack M，et al.Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery［J］.N Engl J Med，2010，363：1597-1607.
［2］Pellikka PA，Sarano ME，Nishimura RA，et al.Outcome of 622 Adults With Asymptomatic，Hemodynamically Significant Aortic Stenosis During Prolonged Follow-Up［J］.Circulation，2005，111：3290-3295.
［3］Kang DH，Park SJ，Rim JH，et al.Early surgery versus conventional treatment in asymptomatic very severe aortic stenosis［J］.Circulation，2010，121（13）：1502-1509.
［4］Nishimura RA，Otto CM，Bonow RO，et al.American College of Cardiology/American Heart Association Task Force on Practice Guidelines.2014 AHA/ACC guideline for the management of patients with valvular heart disease：executive summary：a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines［J］.J Am Coll Cardiol，2014，63（22）：2438-2488.
［5］Holmes DR Jr，Mack MJ，Kaul S，et al.2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement［J］.J Am Coll Cardiol，2012，59：1200-1254.
［6］McCrindle BW.Independent predictors of immediate results of percutaneous balloon aortic valvotomy in children［J］.Am J C ardiol，1996，77：286-293.
［7］Otto CM，Mickel MC，Kennedy JW，et al.Three year outcome after balloon aortic valvuloplasty：insights into prognosis of valvular aortic stenosis［J］.Circulation，1994，89：642-650.
［8］Pellikka PA，Nishimura RA，Bailey KR，et al.The natural history of adults with asymptomatic，hemodynamically significant aortic stenosis［J］.J Am Coll Cardiol，1990，15：1012-1017.
［9］Kelly TA，Rothbart RM，Cooper CM，et al.Comparison of outcome of asymptomatic to symptomatic patients older than 20 years of age with valvular aortic stenosis［J］.Am J Cardiol，1988，61：123-130.
［10］Pellikka PA，Nishimura RA，Bailey KR，et al.Natural history of 610 adults with asymptomatic hemodynamically significant aortic stenosis over prolonged follow up（abstract）［J］.J Am Coll Cardiol，2001，37（suppl A）：489A.(https://www.daowen.com)
［11］Thai HM，Gore JM.Prosthetic heart valves［A］.In：Alpert J S，Dalen J E，Tahimtoola SH，eds.Valvular heart disease［C］.3rd ed.Philadelphia：Lippincott Williams &Wilkins，2000，393-407.
［12］Connolly HM，Oh J K，Schaff HV，et al.Severe aortic stenosis with low transvalvular gradient and severe left ventricular dysfunction：result of aortic valve replacement in 52 patients［J］.Circulation，2000，101：1940-1946.
［13］Thourani VH，Ailawadi G，Szeto WY，et al.Outcomes of surgical aortic valve replacement in high-risk patients：a multiinstitutional study［J］.Ann Thorac Surg，2011，91：49-55.
［14］Bach DS，Cimino N，Deeb GM.Unoperated patients with severe aortic stenosis［J］.J Am Coll Cardiol，2007，50：2018-2019.
［15］Bach DS，Siao D，Girard SE，et al.Evaluation of patients with severe symptomatic aortic stenosis who do not undergo aortic valve replacement：the potential role of subjectively overestimated operative risk［J］.Circ Cardiovasc Qual Outcomes，2009，2：533-539.
［16］Dua A，Dang P，Shaker R，et al.Barriers to surgery in severe aortic stenosis patients with Class I indications for aortic valve replacement［J］.J Heart Valve Dis，2011，20：396-400.
［17］Iung B，Baron G，Butchart EG，et al.A prospective survey of patients with valvular heart disease in Europe：the Euro Heart Survey on Valvular Heart Disease［J］.Eur Heart J，2003，24：1231-1243.
［18］Iung B，Cachier A，Baron G，et al.Decision-making in elderly patients with severe aortic stenosis：why are so many denied surgery？［J］.Eur Heart J，2005，26：2714-2720.
［19］Otto CM，Mickel MC，Kennedy JW，et al.Three-year outcome after balloon aortic valvuloplasty.Insights into prognosis of valvular aortic stenosis［J］.Circulation，1994，89：642-650.